Seoul National University Children's Hospital, Department of Thoracic and Cardiovascular Surgery, College of Medicine, Seoul National University, 101, Daehak-ro, Jongno-gu, Seoul, Republic of Korea.
Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Bucheon, Republic of Korea.
Pediatr Cardiol. 2022 Jan;43(1):74-81. doi: 10.1007/s00246-021-02694-y. Epub 2021 Jul 31.
Pulmonary valve replacement (PVR) is often performed in patients with repaired tetralogy of Fallot (TOF). Concomitant tricuspid valvuloplasty (TVP) in those with tricuspid regurgitation (TR) at the time of PVR is still controversial.
We retrospectively reviewed clinical records of patients who underwent PVR between 2001 and 2012. We analyzed the impact of concomitant TVP on the tricuspid valve function and right ventricle function and size in mid-term.
119 patients with mild to moderate TR at the time of PVR were enrolled. 33 patients underwent concomitant TVP (TVP group) and 86 patients underwent PVR alone (no-TVP group). There was a significant reduction of TR (p < 0.001) and right ventricular end-diastolic volume index (RVEDVi) (p < 0.001). However, in patients who showed prosthetic pulmonary valve (PV) failure at the last follow-up, there was no significant decrease in TR regardless of concomitant TVP. In the patients with preserved prosthetic PV function, TR was significantly improved (p < 0.001 in both groups). The multivariable analysis showed that significant risk factors for recurrence of significant TR were preoperative moderate TR and prosthetic PV failure.
After PVR in repaired TOF patients, there was an improvement in the degree of TR and the RVEDVi. Concomitant TVP at the time of PVR may not be able to prevent the recurrence of TR when prosthetic PV failure occurs; however, it may effectively preserve tricuspid valve function until that time.
肺动脉瓣置换术(PVR)常应用于修复性法洛四联症(TOF)患者。对于合并三尖瓣反流(TR)的患者,同期行三尖瓣成形术(TVP)仍存在争议。
我们回顾性分析了 2001 年至 2012 年间接受 PVR 的患者的临床资料。分析同期 TVP 对中期三尖瓣功能和右心室功能及大小的影响。
共纳入 119 例 PVR 时轻度至中度 TR 的患者。33 例同期行 TVP(TVP 组),86 例行单纯 PVR(无 TVP 组)。TR(p<0.001)和右心室舒张末期容积指数(RVEDVi)(p<0.001)显著降低。然而,在最后一次随访时出现人工肺动脉瓣(PV)功能障碍的患者,无论同期是否行 TVP,TR 均无显著下降。在保留人工 PV 功能的患者中,TR 显著改善(两组均 p<0.001)。多变量分析显示,术前中度 TR 和人工 PV 功能障碍是 TR 复发的显著危险因素。
修复性 TOF 患者行 PVR 后,TR 程度和 RVEDVi 改善。当人工 PV 功能障碍时,同期行 PVR 可能无法预防 TR 复发,但可在此之前有效维持三尖瓣功能。