The Cornea Institute, L V Prasad Eye Institute, Hyderabad, India.
Centre for Innovation, L V Prasad Eye Institute, Hyderabad, India.
Semin Ophthalmol. 2022 Feb 17;37(2):232-240. doi: 10.1080/08820538.2021.1958875. Epub 2021 Aug 1.
To assess the utility of a universal smartphone attachment to capture images of the anterior segment of the eye, we conducted a retrospective analysis of 344 images captured using a smartphone by the patients to identify factors affecting image quality, such as lack of perspective, lack of focus, improper illumination, and resolution. Based on this analysis, a universal smartphone attachment named GrabiLite and a protocol for anterior segment imaging were designed and validated in the first prospective arm of 60 patients. These images were then compared with the same eyes imaged on the gold standard slit-lamp photography. In the second prospective arm, nine patients were trained to use the Grabi Lite with the imaging protocol, and the images were assessed for utility in arriving at a diagnosis. A total of 178 images were analyzed using a questionnaire by masked observers. The images were evaluated based on their quality and suitability in clinical decision-making, risk stratification for triage for referral to a tertiary eye care centre. The quality of 344 images captured by patients using only their smartphone was rated as good 24 (7%), average 209 (60.8%), and poor in 111 (32.2%). Of these, 55 (16%) images were deemed suitable for clinical decision-making, and 224 (65.6%) images were adequate for risk stratification. Lack of perspective, focus, illumination, and resolution were seen in 167 (51.2%), 284 (87.1%), 226 (69.3%), and 126 (38.7%) images, respectively. These metrics improved in the next iteration of 178 images captured by patients using Grabi Lite + imaging protocol to good 103 (57%), average 58 (32.6%), and bad 17 (19.6%) ( < .001 using chi-square test). Images deemed suitable for clinical decision-making, and risk stratification for triage also improved to 80 (45%), 158 (88.8%) ( < .001 using chi-square test), respectively. Adherence to protocol was seen in 98 (55.5%) images, of which all were suitable for risk stratification, while of these images, 66 (67.3%) were eligible for clinical decision making. In comparison with slit-lamp photography, out of 120 responses by masked observers to images captured by Grabi Lite with the imaging protocol, 63 (52.85%) were suitable for clinical decision-making, and 68 (57%) were graded to be between 70 and 99% of the quality of the slit lamp photographs. The Grabi lite with imaging protocol training is an effective tool to improve anterior segment imaging, potentially allowing smartphone use for teleconsultations. This device may serve as a universal solution for all smartphones with the patient as the user and is of value in the future of tele-ophthalmology.
为了评估通用智能手机附件捕捉眼前节图像的效用,我们对 344 张由患者使用智能手机拍摄的图像进行了回顾性分析,以确定影响图像质量的因素,如缺乏透视、焦点不准、光照不当和分辨率低。基于此分析,我们设计并验证了一种名为 GrabiLite 的通用智能手机附件和眼前节成像方案,并在 60 名患者的前瞻性第一部分中进行了验证。然后,将这些图像与相同眼睛的金标准裂隙灯摄影图像进行了比较。在第二部分前瞻性研究中,对 9 名使用 Grabi Lite 和成像方案的患者进行了培训,并评估了这些图像在诊断中的应用效果。共有 178 张图像由盲法观察者使用问卷进行了分析。这些图像根据其质量和在临床决策中的适用性进行了评估,包括用于分诊的风险分层,以确定是否转诊到三级眼科中心。仅使用智能手机拍摄的 344 张图像的质量被评为良好 24 张(7%)、一般 209 张(60.8%)和差 111 张(32.2%)。其中,55 张(16%)图像被认为适合临床决策,224 张(65.6%)图像适合风险分层。在接下来的 178 张由患者使用 Grabi Lite + 成像方案拍摄的图像中,分别有 167 张(51.2%)、284 张(87.1%)、226 张(69.3%)和 126 张(38.7%)图像存在缺乏透视、焦点、光照和分辨率的问题(卡方检验,<.001)。使用 Grabi Lite + 成像方案拍摄的下一组 178 张图像中,质量改善为良好 103 张(57%)、一般 58 张(32.6%)和差 17 张(19.6%)(卡方检验,<.001)。被认为适合临床决策和用于分诊的风险分层的图像也分别提高到 80 张(45%)和 158 张(88.8%)(卡方检验,<.001)。在 98 张(55.5%)遵守方案的图像中,所有图像都适合风险分层,而在这些图像中,有 66 张(67.3%)适合临床决策。与裂隙灯摄影相比,在 120 张由 Grabi Lite 拍摄的图像中,有 63 张(52.85%)被认为适合临床决策,68 张(57%)被评为与裂隙灯照片质量在 70%至 99%之间。带有成像方案的 Grabi Lite 是一种有效的眼前节成像改善工具,有可能允许使用智能手机进行远程咨询。该设备可作为所有智能手机的通用解决方案,用户为患者,在远程眼科领域具有重要价值。