Nikoo Mohammad Hossein, Estedal Alireza, Khatami Kiana, Pakfetrat Maryam, Arjangzadeh Alireza, Boogar Shahrokh Sadeghi, Danesh Sina, Heydari Seyed Taghi
Non-Communicable Disease Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.
Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Cardiol Res Pract. 2021 Jul 19;2021:5541385. doi: 10.1155/2021/5541385. eCollection 2021.
point and coved ST elevation in right precordial leads (not produced by coronary artery disease) are still a matter of challenge, especially when resembling Brugada patients. This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be reported in some severely ill patients before ventricular fibrillation. This study investigated the relationship between the electrocardiograms with demographic and laboratory data and also analyzed their association with mortality rate among patients with methanol poisoning.
The sample consisted of 356 patients who were hospitalized with a diagnosis of methanol poisoning in Faghihi and Namazi Hospitals in Shiraz, Southern Iran, in March and April 2020. In this period, a major outbreak of methanol poisoning had occurred in this area. Furthermore, the study used the data on any recorded complications or mortality during hospital course.
The ECG (BrP) was observed in a total of 20 (5.6%) patients. Its presence was associated with increased mortality, Glasgow coma scale score <3, and blood sugar levels and was inversely associated with PH, O saturation, and calcium levels ( < 0.05).
This study found that certain ECG patterns and laboratory data can be used as prognostic factors of morbidity and mortality in patients with methanol intoxication. Electrocardiography machines are widely available tools, which can be easily used for risk stratification based on the presence of Brugada approximating electrocardiograms among patients with methanol intoxication.
右胸前导联的尖峰和穹窿型ST段抬高（非冠状动脉疾病所致）仍是一个具有挑战性的问题，尤其是当与Brugada综合征患者相似时。在无心脏性猝死家族史的无症状个体中，这种临床情况在一些重症患者发生心室颤动之前就会出现。本研究调查了心电图与人口统计学和实验室数据之间的关系，并分析了它们与甲醇中毒患者死亡率的关联。
样本包括2020年3月和4月在伊朗南部设拉子的法吉希医院和纳马齐医院因甲醇中毒住院的356例患者。在此期间，该地区发生了一次甲醇中毒大暴发。此外，本研究使用了住院期间记录的任何并发症或死亡率数据。
共20例（5.6%）患者观察到心电图（Brugada综合征样心电图）。其出现与死亡率增加、格拉斯哥昏迷量表评分<3以及血糖水平相关，与pH值、血氧饱和度和钙水平呈负相关（P<0.05）。
本研究发现，某些心电图模式和实验室数据可作为甲醇中毒患者发病和死亡的预后因素。心电图机是广泛可用的工具，可根据甲醇中毒患者中出现的类似Brugada综合征的心电图轻松用于风险分层。
