新型冠状病毒感染后急性视网膜坏死的再激活
Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection.
作者信息
Gonzalez Monica P, Rios Radames, Pappaterra Mariella, Hernandez Miguel, Toledo Allison, Santos Carmen, Emanuelli Andres, Kurup Shree K, Oliver Armando L
机构信息
University of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, Paseo Dr. Jose Celso Barbosa, San Juan 00921, USA.
Ponce Health Sciences University School of Medicine, 388 Zona Industrial Reparada 2, Ponce, PR 00716, USA.
出版信息
Case Rep Ophthalmol Med. 2021 Jul 16;2021:7336488. doi: 10.1155/2021/7336488. eCollection 2021.
PURPOSE
To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection.
METHODS
Observational case report. . A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA.
CONCLUSIONS
Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis.
目的
报告1例新型冠状病毒2019感染后急性视网膜坏死复发的病例。
方法
观察性病例报告。一名32岁女性，既往有因坏死性疱疹性视网膜炎导致左眼视网膜脱离病史，现主诉右眼视力下降、疼痛、眼红和畏光。眼科检查发现符合右眼急性视网膜坏死的表现。右眼玻璃体的聚合酶链反应（PCR）分析显示单纯疱疹病毒2型（HSV-2）呈阳性。使用逆转录（RT）-PCR进行的2019冠状病毒病（COVID-19）筛查试验显示新型冠状病毒2019（SARS-CoV-2）RNA呈阳性。
结论
我们的病例提示，COVID-19可能导致潜伏的HSV感染重新激活，使既往有HSV相关急性视网膜坏死病史的患者出现对侧受累。
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