• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Simultaneous Determination of Hydrochlorothiazide and Losartan Potassium in Pharmaceutical Product by UV-Vis Spectrophotometric Method with Kalman Filter Algorithm.

作者信息

Binh Tran Thuc, Phuong Tram Le Thi, Van Hop Nguyen, Giang Chau Nguyen Dang, Luu Nguyen Duy, Quynh Trang Nguyen Thi

机构信息

University of Sciences, Hue University, Hue 530000, Vietnam.

Da Nang University of Medical Technology and Pharmacy, Da Nang 550000, Vietnam.

出版信息

J Anal Methods Chem. 2021 Jul 20;2021:2754133. doi: 10.1155/2021/2754133. eCollection 2021.

DOI:10.1155/2021/2754133
PMID:34336356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8318744/
Abstract

In this paper, hydrochlorothiazide (HCT) and losartan potassium (LSP) in tablets are simultaneously determined with UV-Vis spectrophotometry and chemometrics without separation. The spectra of standard and sample solutions were recorded in the wavelength from 220 to 300 nm at 1.0 nm intervals. The concentrations of HCT and LSP in the sample solutions were computed with the Kalman filter algorithm written on the Microsoft Excel 2016 and Visual Basic for Applications (VBA) platform. The method validation was determined via the accuracy and repeatability of measurements when analyzing HCT and LSP in the Splozarsin Plus tablet and comparing the mean values of their contents in the sample with those analyzed with HPLC. The proposed method is simple with a low cost compared with the standard HPLC method.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/2f20cd780f94/JAMC2021-2754133.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/01519a673d7e/JAMC2021-2754133.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/45a620ffc813/JAMC2021-2754133.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/2f20cd780f94/JAMC2021-2754133.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/01519a673d7e/JAMC2021-2754133.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/45a620ffc813/JAMC2021-2754133.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ea1/8318744/2f20cd780f94/JAMC2021-2754133.003.jpg

相似文献

1
Simultaneous Determination of Hydrochlorothiazide and Losartan Potassium in Pharmaceutical Product by UV-Vis Spectrophotometric Method with Kalman Filter Algorithm.
J Anal Methods Chem. 2021 Jul 20;2021:2754133. doi: 10.1155/2021/2754133. eCollection 2021.
2
Simultaneous Determination of Paracetamol, Ibuprofen, and Caffeine in Tablets by Molecular Absorption Spectroscopy Combined with Classical Least Square Method.分子吸收光谱法结合经典最小二乘法同时测定片剂中的对乙酰氨基酚、布洛芬和咖啡因。
Molecules. 2022 Apr 20;27(9):2657. doi: 10.3390/molecules27092657.
3
Spectrophotometric and HPLC methods for simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazide in tablets.分光光度法和高效液相色谱法同时测定片剂中苯磺酸氨氯地平、氯沙坦钾和氢氯噻嗪的含量。
Indian J Pharm Sci. 2010 Jan;72(1):136-40. doi: 10.4103/0250-474X.62239.
4
Analysis of binary mixtures of losartan potassium and hydrochlorothiazide by using high performance liquid chromatography, ratio derivative spectrophotometric and compensation technique.采用高效液相色谱法、比率导数分光光度法和补偿技术对氯沙坦钾和氢氯噻嗪二元混合物进行分析。
J Pharm Biomed Anal. 2001 Feb;24(4):603-11. doi: 10.1016/s0731-7085(00)00434-9.
5
A multivariate approach for the simultaneous determination of losartan potassium and hydrochlorothiazide in a combined pharmaceutical tablet formulation.
Anal Bioanal Chem. 2008 Aug;391(8):2949-55. doi: 10.1007/s00216-008-2180-z. Epub 2008 Jun 5.
6
Development and validation of an UV derivative spectrophotometric determination of Losartan potassium in tablets.紫外衍生化分光光度法测定片剂中氯沙坦钾的方法开发与验证
J Pharm Biomed Anal. 2003 Sep 19;33(2):175-80. doi: 10.1016/s0731-7085(03)00347-9.
7
Simultaneous spectrophotometric determination of losartan potassium, amlodipine besilate and hydrochlorothiazide in pharmaceuticals by chemometric methods.采用化学计量学方法同时分光光度法测定药物中的氯沙坦钾、氨氯地平贝那普利和氢氯噻嗪。
Acta Pharm. 2010 Jun;60(2):141-52. doi: 10.2478/v10007-010-0017-8.
8
Simultaneous spectrophotometric estimation of Hydrochlorothiazide, Atenolol and Losartan potassium in tablet dosage form.片剂剂型中氢氯噻嗪、阿替洛尔和氯沙坦钾的同步分光光度法测定
Hindustan Antibiot Bull. 2009;51(1-4):33-8.
9
Simultaneous determination of hydrochlorothiazide and losartan potassium in tablets by high-performance low-pressure chromatography using a multi-syringe burette coupled to a monolithic column.使用与整体柱相连的多注射器滴定管通过高效低压色谱法同时测定片剂中的氢氯噻嗪和氯沙坦钾。
Anal Bioanal Chem. 2008 Jul;391(6):2349-56. doi: 10.1007/s00216-008-2172-z. Epub 2008 May 24.
10
[Spectra derivative kalman filter method for simultaneous spectrophotometric determination of phenol, 2-chlorophenol and 2,4-dichlorophenol].光谱导数卡尔曼滤波法同时分光光度法测定苯酚、2-氯苯酚和2,4-二氯苯酚
Guang Pu Xue Yu Guang Pu Fen Xi. 2007 Mar;27(3):560-4.

本文引用的文献

1
Simultaneous Determination of Hydrochlorothiazide and Losartan Potassium in Osmotic Pump Tablets by Microemulsion Liquid Chromatography.微乳液液相色谱法同时测定渗透泵片中氢氯噻嗪和氯沙坦钾的含量
J Chromatogr Sci. 2016 Sep;54(8):1415-20. doi: 10.1093/chromsci/bmw101. Epub 2016 Jun 21.
2
Estimation of Amlodipine Besylate, Valsartan and Hydrochlorothiazide in Bulk Mixture and Tablet by UV Spectrophotometry.紫外分光光度法测定苯磺酸氨氯地平、缬沙坦和氢氯噻嗪的原料药混合物及片剂含量
Indian J Pharm Sci. 2012 Jan;74(1):18-23. doi: 10.4103/0250-474X.102538.
3
A multivariate approach for the simultaneous determination of losartan potassium and hydrochlorothiazide in a combined pharmaceutical tablet formulation.
Anal Bioanal Chem. 2008 Aug;391(8):2949-55. doi: 10.1007/s00216-008-2180-z. Epub 2008 Jun 5.
4
Analysis of binary mixtures of losartan potassium and hydrochlorothiazide by using high performance liquid chromatography, ratio derivative spectrophotometric and compensation technique.采用高效液相色谱法、比率导数分光光度法和补偿技术对氯沙坦钾和氢氯噻嗪二元混合物进行分析。
J Pharm Biomed Anal. 2001 Feb;24(4):603-11. doi: 10.1016/s0731-7085(00)00434-9.