新生马驹中性粒细胞迁移、吞噬作用及杀菌能力的评估
Assessment of neutrophil migration, phagocytosis and bactericidal capacity in neonatal foals.
作者信息
Morris D D, Gaulin G, Strzemienski P J, Spencer P
机构信息
Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
出版信息
Vet Immunol Immunopathol. 1987 Nov;16(3-4):173-84. doi: 10.1016/0165-2427(87)90016-x.
Comparison of neutrophil function was made between 8 clinically normal pony foals (3 to 7 days of age), and their dams. Random migration, stimulated migration to zymosan-activated serum, bacterial phagocytosis and bactericidal capacity of neutrophils were determined in vitro. Random migration was greater (P less than 0.01) and stimulated migration was less (P less than 0.01) in foals than in their dams. Bacterial phagocytosis and bactericidal capacity of neutrophils were not different (P greater than 0.05) between foals and mares. Results of this study suggested that neonatal foals have altered neutrophil locomotion, when compared to their dams.
对8匹临床正常的小马驹（3至7日龄）及其母马的中性粒细胞功能进行了比较。体外测定了中性粒细胞的随机迁移、对酵母聚糖激活血清的趋化迁移、细菌吞噬作用和杀菌能力。小马驹的随机迁移率更高（P<0.01），趋化迁移率更低（P<0.01）。小马驹和母马的中性粒细胞细菌吞噬作用和杀菌能力没有差异（P>0.05）。本研究结果表明，与母马相比，新生小马驹的中性粒细胞运动发生了改变。
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