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有丝分裂纺锤体中的电位类型。

Types of potentials in a mitotic spindle.

作者信息

Nemchen Yelena, Hallford Randal, Sharma Preet

机构信息

Non-Linear Science Research Group, Department of Chemistry & Physics, Midwestern State University, United States of America.

出版信息

Biochem Biophys Rep. 2021 Jul 17;27:101076. doi: 10.1016/j.bbrep.2021.101076. eCollection 2021 Sep.

DOI:10.1016/j.bbrep.2021.101076
PMID:34337166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8313597/
Abstract

The dynamics of a mitotic spindle is very important to understand if the functioning of mitosis has to be understood and defined very accurately. There are a number of forces involved in such a process. Despite of the fact that there have been numerous studies done on the functioning of a mitotic spindle, there is still not a very precise understanding of this system and how it behaves. This study aims at understanding and expressing all the possible potentials which might be responsible in a mitotic spindle and its mechanism.

摘要

如果要非常准确地理解和界定有丝分裂的功能,那么了解有丝分裂纺锤体的动力学就非常重要。这一过程涉及多种力。尽管已经对有丝分裂纺锤体的功能进行了大量研究,但对这个系统及其行为仍没有非常精确的理解。本研究旨在了解和阐述可能与有丝分裂纺锤体及其机制相关的所有潜在因素。

相似文献

1
Types of potentials in a mitotic spindle.有丝分裂纺锤体中的电位类型。
Biochem Biophys Rep. 2021 Jul 17;27:101076. doi: 10.1016/j.bbrep.2021.101076. eCollection 2021 Sep.
2
Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling.通过计算建模分析染色体的双定向和双极纺锤体组装的机制。
Elife. 2020 Feb 13;9:e48787. doi: 10.7554/eLife.48787.
3
JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis.JMJD5(含Jumonji结构域蛋白5)与纺锤体微管相关联,是正常有丝分裂所必需的。
J Biol Chem. 2016 Feb 26;291(9):4684-97. doi: 10.1074/jbc.M115.672642. Epub 2015 Dec 28.
4
The structure of the mitotic spindle and nucleolus during mitosis in the amebo-flagellate Naegleria.在阿米巴-鞭毛虫纳氏疟原虫有丝分裂过程中,有丝分裂纺锤体和核仁的结构。
PLoS One. 2012;7(4):e34763. doi: 10.1371/journal.pone.0034763. Epub 2012 Apr 6.
5
Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis.核有丝分裂器蛋白(NuMA)中预测的p34cdc2磷酸化位点发生突变,会损害有丝分裂纺锤体的组装并阻断有丝分裂。
J Cell Sci. 1995 Feb;108 ( Pt 2):621-33. doi: 10.1242/jcs.108.2.621.
6
Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage.Bcl-xL的表达与p53缺失协同作用可克服有丝分裂纺锤体损伤诱导的细胞周期检查点。
Genes Dev. 1996 Oct 15;10(20):2621-31. doi: 10.1101/gad.10.20.2621.
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The evolution of spindles and their mechanical implications for cancer metastasis.纺锤体的进化及其对癌症转移的机械影响。
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Budding yeast Swe1 is involved in the control of mitotic spindle elongation and is regulated by Cdc14 phosphatase during mitosis.出芽酵母Swe1参与有丝分裂纺锤体伸长的控制,并在有丝分裂期间受Cdc14磷酸酶调节。
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Helical Twist and Rotational Forces in the Mitotic Spindle.有丝分裂纺锤体中的螺旋扭曲和旋转力。
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Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation.氧化应激通过抑制与极光激酶A相关的有丝分裂纺锤体形成来诱导有丝分裂停滞。
Free Radic Biol Med. 2017 Feb;103:177-187. doi: 10.1016/j.freeradbiomed.2016.12.031. Epub 2016 Dec 23.

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Effective chemical potential for non-equilibrium systems and its application to molecular beam epitaxy of BiSe.
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Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos by four-dimensional microscopy-based motion analysis.通过基于四维显微镜的运动分析在活体果蝇胚胎中测量染色体弹性和有丝分裂极向喷射力。
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