Department Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.
Cell Rep Med. 2021 Jul 21;2(7):100347. doi: 10.1016/j.xcrm.2021.100347. eCollection 2021 Jul 20.
Esmaili et al. conducted co-expression network analysis to uncover core homeostatic modules critical to a broad spectrum of liver diseases in mouse and human. Perturbation state of core modules may underlie disease stages across species and serve as therapeutic targets.
Esmaili 等人进行了共表达网络分析,以揭示对小鼠和人类广泛肝脏疾病至关重要的核心内稳模块。核心模块的扰动状态可能是跨物种疾病阶段的基础,并可作为治疗靶点。