Yip Tiffany, Chen Mingzhang, Wang Yijie, Slopen Natalie, Chae David, Priest Naomi, Williams David
Fordham University, Department of Psychology, 441 E. Fordham Road, 226 Dealy Hall, Bronx, NY, 10458, USA.
Michigan State University, Human Development and Family Studies, 552 West Circle Drive, East Lansing, MI, 48824, USA.
Compr Psychoneuroendocrinol. 2021 Feb;5. doi: 10.1016/j.cpnec.2020.100021. Epub 2020 Dec 11.
Self-reported experiences of discrimination and sleep dysfunction have both been shown to adversely impact biological functioning; however, few studies have examined how they are jointly associated with health. The current study draws from two samples of the Midlife in the United States (MIDUS) data (n = 617 participants; 59.8% female; 72.3% White and 27.7% African American; Age: Mean = 52.6, = 12.22) to identify profiles of sleep (duration, variability, onset latency, wake after sleep onset, naps) and discrimination (everyday, lifetime, impact). Associations with latent profiles of biomarkers of inflammation (CRP, fibrinogen, IL-6) and endocrine stress (cortisol, epinephrine, norepinephrine) were examined. Three profiles were identified for sleep/discrimination () and for biomarkers (). Chi-square analyses indicated that adults in the profile were more likely to be in the profile but less likely to be in the profile. Adults in the profile were more likely to be in the profile. Adults in the profile were less likely to be in the profile but more likely to be in the profile. The current study identified configurations of sleep and discrimination among midlife adults which were associated with profiles of biological risk. The findings provide implications for identifying individuals who may be at increased risk of developing stress-related tertiary outcomes of morbidity and disease.
自我报告的歧视经历和睡眠功能障碍均已被证明会对生物功能产生不利影响；然而，很少有研究探讨它们如何与健康共同相关。当前的研究从美国中年（MIDUS）数据的两个样本中抽取（n = 617名参与者；59.8%为女性；72.3%为白人，27.7%为非裔美国人；年龄：平均值 = 52.6，标准差 = 12.22），以确定睡眠（时长、变异性、入睡潜伏期、睡眠中觉醒、小睡）和歧视（日常、一生、影响）的特征。研究了与炎症生物标志物（CRP、纤维蛋白原、IL - 6）和内分泌应激（皮质醇、肾上腺素、去甲肾上腺素）的潜在特征的关联。确定了睡眠/歧视的三种特征以及生物标志物的三种特征。卡方分析表明，处于第一种睡眠/歧视特征的成年人更有可能处于第一种生物标志物特征，但不太可能处于第二种生物标志物特征。处于第二种睡眠/歧视特征的成年人更有可能处于第一种生物标志物特征。处于第三种睡眠/歧视特征的成年人不太可能处于第一种生物标志物特征，但更有可能处于第二种生物标志物特征。当前的研究确定了中年成年人中睡眠和歧视的组合，这些组合与生物风险特征相关。这些发现为识别可能面临与压力相关的发病和疾病三级后果风险增加的个体提供了启示。
