Henckes Nicole Andréa Corbellini, Faleiro Dalana, Chuang Laura Chao, Cirne-Lima Elizabeth Obino
Programa de Pós-Graduação em Ciências da Saúde-Ginecologia e Obstetrícia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Laboratório de Embriologia e Diferenciação Celular, Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Cell Regen. 2021 Aug 2;10(1):26. doi: 10.1186/s13619-021-00088-2.
Tissue engineering has provided new treatment alternatives for tissue reconstruction. Advances in the tissue engineering field have resulted in mechanical support and biological substitutes to restore, maintain or improve tissue/organs structures and functions. The application of tissue engineering technology in the vaginal reconstruction treatment can not only provide mechanical requirements, but also offer tissue repairing as an alternative to traditional approaches. In this review, we discuss recent advances in cell-based therapy in combination with scaffolds strategies that can potentially be adopted for gynaecological transplantation.
组织工程为组织重建提供了新的治疗选择。组织工程领域的进展带来了机械支撑和生物替代物，以恢复、维持或改善组织/器官的结构和功能。组织工程技术在阴道重建治疗中的应用不仅能满足机械需求，还能作为传统方法的替代方案提供组织修复。在本综述中，我们讨论了基于细胞的治疗与支架策略的最新进展，这些策略可能适用于妇科移植。
