Wu Xiaotong, Jia YuanYuan, Sun Xiuli, Wang Jianliu
Department of Obstetrics and Gynecology Peking University People's Hospital Beijing P. R. China.
Beijing Key Laboratory of Female Pelvic Floor Disorders Beijing P. R. China.
Eng Life Sci. 2020 Apr 14;20(7):275-286. doi: 10.1002/elsc.202000003. eCollection 2020 Jul.
Pelvic organ prolapse is a common and frequently occurring disease in middle-aged and elderly women. Mesh implantation is an ideal surgical treatment. The polypropylene mesh commonly used in clinical practice has good mechanical properties, but there are long-term complications. The application of tissue engineering technology in the treatment of pelvic organ prolapse disease can not only meet the mechanical requirements of pelvic floor support, but also be more biocompatible than traditional polypropylene mesh, and can promote tissue repair to a certain extent. In this paper, the progress of tissue engineering was summarized to understand the application of tissue engineering in the treatment of pelvic organ prolapse disease and will help in research.
盆腔器官脱垂是中老年女性常见且多发的疾病。网状物植入是一种理想的外科治疗方法。临床实践中常用的聚丙烯网状物具有良好的机械性能，但存在长期并发症。组织工程技术在盆腔器官脱垂疾病治疗中的应用不仅能满足盆底支撑的机械要求，而且比传统聚丙烯网状物具有更好的生物相容性，并且在一定程度上能促进组织修复。本文总结了组织工程的进展，以了解组织工程在盆腔器官脱垂疾病治疗中的应用，并将有助于相关研究。
