Liebetrau G, Pielesch W
Lungenklinik, Zentralklinik für Herz- und Lungenkrankheiten Bad Berka.
Z Gesamte Inn Med. 1987 Oct 15;42(20):589-91.
The causes for alveolitis and lung fibroses are very multifarious. In the scale of the contaminant factors the medicaments occupy only a small sector. Nevertheless, the knowledge of such a side effect is significant on account of the often unfavourable prognosis of the alveolitis. When medicaments with wellknown ability of impairment are administered (e.g. cytostatic drugs, antiarrhythmic drugs etc.) a narrow-meshed observation with suitable control parameters is to be demanded. Only the timely recognition of a side effect of a medicament in the lung structure can prevent the fatal change into a pulmonary fibrosis. In 801 alveolitis and lung fibrosis diagnosed in our clinic 10 times a medicament was established as cause.
肺泡炎和肺纤维化的病因非常多样。在污染物因素范围内，药物仅占一小部分。然而，鉴于肺泡炎通常预后不佳，了解这种副作用具有重要意义。当使用具有已知损害能力的药物（如细胞毒性药物、抗心律失常药物等）时，需要进行细致观察并设置合适的对照参数。只有及时识别药物对肺部结构的副作用，才能防止其发展为致命的肺纤维化。在我们诊所诊断的801例肺泡炎和肺纤维化病例中，有10次确定药物为病因。
