[Principles of modern antibiotic therapy in general practice and the clinic].

It is reported on the principles of modern therapy with antibiotics and here above all is referred to the differences in the antibiotic treatment in practice and clinic. Issuing from the infections usually occurring in practice with the spectre of causative agents known in many cases the therapeutic possibilities are discussed also taking into consideration economic points of view. In contrast to this in infections in the clinic, so-called nosocomial diseases, changing situations are present, which need a therapy on the basis of the antibiogramme. In these cases partly also combination therapies for the enlargement of the spectre of action and for the increase of the antibacterial activity are used.