Medical University of South Carolina, Department of Neurosurgery, Charleston, SC 29425, USA.
Medical University of South Carolina, Department of Regenerative Medicine and Bioengineering, Charleston, SC 29425, USA; College of Charleston, Department of Health and Human Performance, Charleston, SC 29425, USA.
Clin Neurol Neurosurg. 2021 Sep;208:106848. doi: 10.1016/j.clineuro.2021.106848. Epub 2021 Jul 27.
Surgical management of lateral lumbar radiculopathy is evolving. TMD (Tubular microdiscectomy) and TELD (Transforaminal endoscopic lumbar discectomy) have emerged as viable MIS treatments. We aim to compare clinical outcomes of both techniques for the treatment of lateral lumbar radiculopathy in relation to pre-operative lumbar foraminal stenosis grade (LFS).
Retrospective observational cohort study of patients with back and leg pain from single level foraminal nerve root compression that underwent TMD or TELD. Data analyzed included pre- and post-operative VAS leg and back pain, MacNab clinical outcome scores, hospital length of stay, complication rates, and operative time. Outcomes were correlated with a pre-operative MRI grading system for LFS.
109 patients were enrolled (71 TELD and 38 TMD). Back and leg VAS pain scores improved in TELD and TMD (p < 0.0001). Patients with grade III stenosis showed significantly higher VAS scores (p < 0.01), and worse functional outcomes at latest follow-up compared with grade I/II LFS. Overall, there was no difference in outcome between procedure groups except that TMD VAS back pain scores were lower than TELD at last follow up (p < 0.05). Clinical outcome comparisons between procedures relating to LFS grade showed higher correlation of LFS to TELD (Spearman's rho (ρ)= 0.342 for TMD and 0.606 TELD). Regression analyses demonstrated correlation between higher-grade foraminal stenosis and poorer outcomes in TELD and TMD.
Both TELD and TMD are viable for treating lateral lumbar radiculopathy. Higher-grade foraminal stenosis can be indicative of poorer outcomes regardless of procedure type, however, the severity of pre-operative LFS correlates with clinical outcomes in TELD more significantly than TMD.
腰椎侧方神经根病变的外科治疗方法在不断发展。TMD(管状微椎间盘切除术)和 TELD(经椎间孔内窥镜下腰椎间盘切除术)已成为可行的微创治疗方法。我们旨在比较这两种技术治疗腰椎侧方神经根病变的临床疗效,与术前腰椎侧方孔狭窄程度(LFS)相关。
回顾性观察队列研究,纳入了单节段椎间孔神经根受压伴腰痛和腿痛的患者,他们接受了 TMD 或 TELD 治疗。分析的数据包括术前和术后 VAS 腿痛和腰痛评分、MacNab 临床疗效评分、住院时间、并发症发生率和手术时间。结果与术前 MRI 分级系统对 LFS 进行了相关性分析。
共纳入 109 例患者(71 例 TELD 和 38 例 TMD)。TELD 和 TMD 组的腰痛和腿痛 VAS 评分均有所改善(p<0.0001)。III 级狭窄患者的 VAS 评分明显更高(p<0.01),且与 I/II 级 LFS 相比,在末次随访时功能结局更差。总体而言,两种手术方法的疗效无差异,但 TMD 组的末次随访 VAS 腰痛评分低于 TELD 组(p<0.05)。与 LFS 分级相关的手术疗效比较显示,LFS 与 TELD 之间的相关性更高(TMD 为 Spearman's rho(ρ)=0.342,TELD 为 0.606)。回归分析表明,在 TELD 和 TMD 中,较高的椎间孔狭窄程度与较差的结果相关。
TELD 和 TMD 均是治疗腰椎侧方神经根病变的可行方法。无论手术类型如何,较高的椎间孔狭窄程度可能预示着较差的预后,但术前 LFS 的严重程度与 TELD 的临床疗效相关性更显著,而与 TMD 的相关性则较低。