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Understanding the "SMART" features of hematopoietic stem cells and beyond.理解造血干细胞的“SMART”特性及其他特性。
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Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.Lrp5 和 Lrp6 对于维持造血干细胞的自我更新和分化是必需的。
FASEB J. 2019 Apr;33(4):5615-5625. doi: 10.1096/fj.201802072R. Epub 2019 Jan 22.
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Phenotypic analysis and isolation of murine hematopoietic stem cells and lineage-committed progenitors.小鼠造血干细胞和定向祖细胞的表型分析与分离
J Vis Exp. 2012 Jul 8(65):3736. doi: 10.3791/3736.
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Non-thermal atmospheric pressure plasma is an excellent tool to activate proliferation in various mesoderm-derived human adult stem cells.非热常压等离子体是一种极好的工具，可以激活各种中胚层来源的人类成体干细胞的增殖。
Free Radic Biol Med. 2019 Apr;134:374-384. doi: 10.1016/j.freeradbiomed.2019.01.032. Epub 2019 Jan 24.
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Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells.一氧化氮对小鼠造血干细胞的功能具有与年龄相关的相反作用。
Stem Cell Res Ther. 2016 Nov 22;7(1):171. doi: 10.1186/s13287-016-0433-x.
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Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cells.视网膜母细胞瘤蛋白（Rb）对于成体造血干细胞的自我更新和多谱系分化并非必需。
Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9057-62. doi: 10.1073/pnas.0603389103. Epub 2006 Jun 5.
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C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence.C/EBPa 控制成人造血干细胞静止期的获得和维持。
Nat Cell Biol. 2013 Apr;15(4):385-94. doi: 10.1038/ncb2698. Epub 2013 Mar 17.
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The Act of Controlling Adult Stem Cell Dynamics: Insights from Animal Models.控制成人干细胞动力学的行为：来自动物模型的见解。
Biomolecules. 2021 Apr 30;11(5):667. doi: 10.3390/biom11050667.
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Regulation of hematopoietic stem cells in the niche.造血干细胞在生态位中的调控。
Sci China Life Sci. 2015 Dec;58(12):1209-15. doi: 10.1007/s11427-015-4960-y. Epub 2015 Nov 13.
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Unique biological properties and application potentials of CD34+ CD38- stem cells from various sources.不同来源的 CD34+ CD38- 干细胞的独特生物学特性和应用潜力。
Taiwan J Obstet Gynecol. 2009 Dec;48(4):356-69. doi: 10.1016/S1028-4559(09)60324-7.
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Towards a blood ecosystem approach to dissect systemic diseases.迈向剖析全身性疾病的血液生态系统研究方法。
Sci China Life Sci. 2024 Jul;67(7):1528-1531. doi: 10.1007/s11427-023-2503-4. Epub 2024 Mar 5.
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Small extracellular vesicles derived from acute myeloid leukemia cells promote leukemogenesis by transferring miR-221-3p.急性髓系白血病细胞来源的小细胞外囊泡通过转移 miR-221-3p 促进白血病发生。
Haematologica. 2024 Oct 1;109(10):3209-3221. doi: 10.3324/haematol.2023.284145.
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Repair of dysfunctional bone marrow endothelial cells alleviates aplastic anemia.功能失调的骨髓内皮细胞的修复可缓解再生障碍性贫血。
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Bone Marrow Immune Microenvironment in Myelodysplastic Syndromes.骨髓增生异常综合征中的骨髓免疫微环境
Cancers (Basel). 2022 Nov 17;14(22):5656. doi: 10.3390/cancers14225656.
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Emerging roles of extracellular vesicles in normal and malignant hematopoiesis.细胞外囊泡在正常和恶性造血中的新兴作用。
J Clin Invest. 2022 Sep 15;132(18):e160840. doi: 10.1172/JCI160840.
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An urgent need for standardization of stem cells and stem cell-derived products toward clinical applications.迫切需要对干细胞及干细胞衍生产品进行标准化，以用于临床应用。
Stem Cells Transl Med. 2021 Nov;10 Suppl 2(Suppl 2):S1-S3. doi: 10.1002/sctm.21-0269.
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Optimizing autologous hematopoietic stem cell transplantation for acute leukemia.优化急性白血病的自体造血干细胞移植。
Stem Cells Transl Med. 2021 Nov;10 Suppl 2(Suppl 2):S75-S84. doi: 10.1002/sctm.21-0176.
本文引用的文献
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Single-cell transcriptomes of peripheral blood cells indicate and elucidate severity of COVID-19.外周血细胞的单细胞转录组表明并阐明了 COVID-19 的严重程度。
Sci China Life Sci. 2021 Oct;64(10):1634-1644. doi: 10.1007/s11427-020-1880-y. Epub 2021 Feb 4.
2
Nociceptive nerves regulate haematopoietic stem cell mobilization.伤害感受神经调节造血干细胞动员。
Nature. 2021 Jan;589(7843):591-596. doi: 10.1038/s41586-020-03057-y. Epub 2020 Dec 23.
3
The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.人类造血干细胞从静止状态向激活状态的转变受动态三维基因组重排的控制。
Cell Stem Cell. 2021 Mar 4;28(3):488-501.e10. doi: 10.1016/j.stem.2020.11.001. Epub 2020 Nov 25.
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Probing the fate of transplanted hematopoietic stem cells: is the combinational approach "FIT" for purpose?探究移植造血干细胞的命运：联合方法是否“适合”目的？
Sci China Life Sci. 2020 Nov;63(11):1755-1758. doi: 10.1007/s11427-020-1786-4. Epub 2020 Aug 25.
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Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding.通过 PolyloxExpress 条形码解析造血干细胞克隆的命运和单细胞转录组。
Cell Stem Cell. 2020 Sep 3;27(3):383-395.e8. doi: 10.1016/j.stem.2020.07.018. Epub 2020 Aug 11.
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Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis.通过单细胞转录组分析追踪移植造血干细胞的分化。
Nat Cell Biol. 2020 Jun;22(6):630-639. doi: 10.1038/s41556-020-0512-1. Epub 2020 May 4.
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Proximity Dependent Biotinylation: Key Enzymes and Adaptation to Proteomics Approaches.邻近依赖性生物素化：关键酶及对蛋白质组学方法的适应。
Mol Cell Proteomics. 2020 May;19(5):757-773. doi: 10.1074/mcp.R120.001941. Epub 2020 Mar 3.
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Reactive Oxygen Species and Nrf2: Functional and Transcriptional Regulators of Hematopoiesis.活性氧物种和 Nrf2：造血的功能和转录调节剂。
Oxid Med Cell Longev. 2019 Nov 18;2019:5153268. doi: 10.1155/2019/5153268. eCollection 2019.
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Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.使用单一UM171扩增脐血的造血干细胞移植：一项单臂1-2期安全性和可行性研究。
Lancet Haematol. 2020 Feb;7(2):e134-e145. doi: 10.1016/S2352-3026(19)30202-9. Epub 2019 Nov 6.
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A mass spectrometry workflow for measuring protein turnover rates in vivo.一种用于测量体内蛋白质周转率的质谱工作流程。
Nat Protoc. 2019 Dec;14(12):3333-3365. doi: 10.1038/s41596-019-0222-y. Epub 2019 Nov 4.
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