The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4.

作者信息

Piskacek Martin, Otasevic Tomas, Repko Martin, Knight Andrea

机构信息

Department of Pathological Physiology, Faculty of Medicine, Masaryk University Brno, Kamenice 5, 625 00, Brno, Czech Republic.

Joint Repair and Regeneration, Orthopaedic Clinic, University Hospital Brno and Faculty of Medicine Masaryk University Brno, Brno, Czech Republic.

出版信息

Stem Cell Rev Rep. 2021 Oct;17(5):1934-1936. doi: 10.1007/s12015-021-10225-8. Epub 2021 Aug 3.

DOI:10.1007/s12015-021-10225-8

PMID:34342803

Abstract

摘要

相似文献

[1]

The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4.

Stem Cell Rev Rep. 2021-10

[2]

Application of the Yamanaka Transcription Factors , , , and from the Laboratory to the Clinic.

Genes (Basel). 2023-8-26

[3]

Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs.

Cell Stem Cell. 2019-12-5

[4]

Selective killing of leukemia cells: Yamanaka factors' new trick.

Stem Cells. 2020-7

[5]

Identification of small activating RNAs that enhance endogenous OCT4 expression in human mesenchymal stem cells.

Stem Cells Dev. 2015-2-1

[6]

Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4.

Cell Rep. 2019-11-12

[7]

Silencing of the transcription factors Oct4, Sox2, Klf4, c-Myc or Nanog has different effect on teratoma growth.

Biochem Biophys Res Commun. 2019-7-25

[8]

Novel AKT phosphorylation sites identified in the pluripotency factors OCT4, SOX2 and KLF4.

Cell Cycle. 2015

[9]

Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming.

Stem Cells. 2009-12

[10]

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules.

Cell Res. 2010-10-19

引用本文的文献

[1]

PRDM1 promotes the stemness of gastric cancer cells by enhancing the transactivation of Myc.

Transl Oncol. 2025-6-17

[2]

FBL promotes hepatocellular carcinoma tumorigenesis and progression by recruiting YY1 to enhance CAD gene expression.

Cell Death Dis. 2025-4-27

[3]

Synthetic transcription factors establish the function of nine amino acid transactivation domains of Komagataella phaffii Mxr1.

J Biol Chem. 2025-3

[4]

Myc 9aaTAD activation domain binds to mediator of transcription with superior high affinity.

Mol Med. 2024-11-13

[5]

DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2.

Nat Commun. 2024-2-16

[6]

Interaction network of human early embryonic transcription factors.

EMBO Rep. 2024-3

[7]

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis.

Nat Cell Biol. 2022-3

本文引用的文献

[1]

Universal two-point interaction of mediator KIX with 9aaTAD activation domains.

J Cell Biochem. 2021-10

[2]

The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs.

Cell Mol Life Sci. 2019-8-2

[3]

The SOXE transcription factors-SOX8, SOX9 and SOX10-share a bi-partite transactivation mechanism.

Nucleic Acids Res. 2019-7-26

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

新学期，新优惠

The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

推荐工具

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献