原发性肝内硬化性胆管炎伴炎性肠病

Primary intrahepatic sclerosing cholangitis with inflammatory bowel disease.

作者信息

Ishikawa T, Aoyama H, Ohtake H, Ohnishi S, Aburatani H, Imawari M, Shiga J, Takaku F

机构信息

Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.

出版信息

Acta Pathol Jpn. 1987 Oct;37(10):1637-43. doi: 10.1111/j.1440-1827.1987.tb02473.x.

DOI:10.1111/j.1440-1827.1987.tb02473.x

PMID:3434285

Abstract

A case of primary intrahepatic sclerosing cholangitis associated with inflammatory bowel disease, which is rare in Japan, is reported. A 16-year-old Japanese boy was admitted to our hospital because of abdominal pain and fever. He was diagnosed as having primary intrahepatic sclerosing cholangitis by endoscopic retrograde cholangiography and liver biopsy. Inflammatory bowel disease was diagnosed by colonoscopy and biopsy of the colonic mucosa. Human lymphocyte antigen typing showed HLA-A2, A-9, -B52 and -DR2.

摘要

本文报告了一例在日本较为罕见的、与炎症性肠病相关的原发性肝内硬化性胆管炎病例。一名16岁的日本男孩因腹痛和发热入院。通过内镜逆行胆管造影和肝活检，他被诊断为原发性肝内硬化性胆管炎。通过结肠镜检查和结肠黏膜活检诊断出炎症性肠病。人类淋巴细胞抗原分型显示为HLA - A2、A - 9、- B52和 - DR2。