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基于最新证据利用现有资源的急性髓系白血病管理方法：沙特血液和骨髓移植学会的共识。

Management Approach to Acute Myeloid Leukemia Leveraging the Available Resources in View of the Latest Evidence: Consensus of the Saudi Society of Blood and Marrow Transplantation.

机构信息

Department of Oncology, Ministry of the National Guard-Health Affairs, Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

出版信息

JCO Glob Oncol. 2021 Jul;7:1220-1232. doi: 10.1200/GO.20.00660.

DOI:10.1200/GO.20.00660
PMID:34343012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8457782/
Abstract

PURPOSE

Acute myeloid leukemia (AML) is the most prevalent acute leukemia in adults and is responsible for the majority of cancer-related mortality. In Saudi Arabia, leukemia is ranked the fifth most prevalent type of malignancy in adults. Our aim is to review existing epidemiologic data in Saudi Arabia and develop consensus guidelines for management of AML.

METHODS

We review literature related to AML epidemiology, treatment patterns, and outcomes in Saudi Arabia, as well as literature related to the current advances in AML treatment. A panel of 10 experts from eight institutions in Saudi Arabia reviewed the literature and developed a consensus statement.

RESULT

We provide an update of the available AML epidemiologic data in Saudi Arabia and describe recent developments in the diagnostic workup, risk stratification, and treatment algorithm. The consensus recommendations for the management of AML in Saudi Arabia were developed.

CONCLUSION

The recommendations are in parallel with the recent international guidelines for the diagnosis and management of AML.

摘要

目的

急性髓系白血病（AML）是成人中最常见的急性白血病，也是导致大多数癌症相关死亡的主要原因。在沙特阿拉伯，白血病在成人恶性肿瘤中排名第五。我们旨在回顾沙特阿拉伯现有的流行病学数据，并制定 AML 管理的共识指南。

方法

我们回顾了与沙特阿拉伯 AML 流行病学、治疗模式和结果相关的文献，以及与 AML 治疗最新进展相关的文献。来自沙特阿拉伯 8 家机构的 10 名专家组成的小组对文献进行了回顾，并达成了共识声明。

结果

我们提供了沙特阿拉伯现有的 AML 流行病学数据的最新信息，并描述了诊断方法、风险分层和治疗方案的最新进展。制定了沙特阿拉伯 AML 管理的共识建议。

结论

这些建议与最近 AML 的国际诊断和管理指南相平行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/e3d86ffcbecc/go-7-go.20.00660-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/fdbccddbaa2c/go-7-go.20.00660-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/7a9a277bc08d/go-7-go.20.00660-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/8afc5e331e7c/go-7-go.20.00660-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/119f40a8e282/go-7-go.20.00660-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/e3d86ffcbecc/go-7-go.20.00660-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/fdbccddbaa2c/go-7-go.20.00660-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/7a9a277bc08d/go-7-go.20.00660-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/8afc5e331e7c/go-7-go.20.00660-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/119f40a8e282/go-7-go.20.00660-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9709/8457782/e3d86ffcbecc/go-7-go.20.00660-g007.jpg

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