Department of Dental Public Health, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Department of Pediatric Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Spec Care Dentist. 2022 Jan;42(1):32-40. doi: 10.1111/scd.12639. Epub 2021 Aug 3.
To identify factors associated with oral health care services for individuals with and without rare genetic diseases.
A cross-sectional study was undertaken, with 140 individuals paired by sex and age (70 with rare genetic diseases and 70 without), aged between 3 and 27 years, and their parents. The sample was selected from two reference hospitals for patients with rare genetic diseases in southeastern Brazil. The parents completed a questionnaire on individual aspects and their child's medical/dental history. Participants who did and did not suffer from rare genetic diseases were examined for dental caries, malocclusion, dental anomalies, and oral hygiene. The theoretical model Directed Acyclic Graphs (DAG) was used to identify possible confounding variables in the association between rare diseases and access to dental care. Descriptive analyses and non-matched and matched logistic regression models (p < 0.05) were carried out.
The chance of individuals without rare genetic disease having access to oral health care service was 5.32 times higher (95% CI 2.35-12.01) than those with such conditions. Individuals who had not suffered upper respiratory tract infections had a 3.16 times greater chance of being in the group with access to oral health care service (95% CI 1.45-6.90).
Individuals with no rare genetic diseases and no history of upper respiratory tract infections had a greater chance of belonging to the group of individuals with access to a dental service. Individuals with rare genetic diseases have less access to oral health care.
确定与患有罕见遗传疾病和不患有罕见遗传疾病的个体的口腔保健服务相关的因素。
进行了一项横断面研究，将 140 名个体按性别和年龄（70 名患有罕见遗传疾病，70 名无）配对，年龄在 3 至 27 岁之间，及其父母。该样本选自巴西东南部两家罕见遗传疾病患者的参考医院。父母填写了一份关于个人方面和孩子医疗/牙科病史的问卷。对患有和不患有罕见遗传疾病的参与者进行了龋齿、错颌、牙齿异常和口腔卫生检查。使用有向无环图（DAG）理论模型来识别罕见疾病与获得牙科保健之间关联的可能混杂变量。进行了描述性分析以及非匹配和匹配的逻辑回归模型分析（p<0.05）。
无罕见遗传疾病的个体获得口腔保健服务的机会是患有此类疾病的个体的 5.32 倍（95%CI 2.35-12.01）。未患上呼吸道感染的个体更有可能获得口腔保健服务（95%CI 1.45-6.90）。
无罕见遗传疾病且无上呼吸道感染史的个体更有可能属于能够获得牙科服务的群体。患有罕见遗传疾病的个体获得口腔保健服务的机会较少。
