Department of Orthopedic, Kaohsiung Municipal Min-Sheng Hospital, Kaohsiung, Taiwan.
Department of Nutrition, Institute of Biomedical Nutrition, Hung-Kuang University, Taichung, Taiwan.
Sci Rep. 2021 Aug 3;11(1):15709. doi: 10.1038/s41598-021-95261-7.
Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. A receiver operating characteristic (ROC) analyses with Youden's Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.
跟骨定量超声（QUS）是骨质疏松症的一种有用的筛查工具，而双能 X 射线吸收法（DXA）是临床实践中的主流方法。我们评估了 QUS 和 DXA 在台湾人群中的相关性。共纳入 772 例患者，并记录了 QUS 和 DXA 髋关节和脊柱 T 评分的人口统计学数据。QUS 与 DXA-髋关节的相关系数为 0.171。对于 DXA-脊柱，总体为 0.135，女性为 0.237，男性为 0.255。使用 DXA-脊柱作为因变量建立逻辑回归模型，分类表显示准确率为 66.2%。采用 Youden 指数的受试者工作特征（ROC）分析显示，预测骨质疏松症的 QUS 最佳截断点为 2.72。本研究表明，QUS 和 DXA 在台湾人群中具有有意义的相关性。因此，用跟骨 QUS 进行骨质疏松症的筛查非常重要。
