Boulay Hugoline, Mazaud-Guittot Séverine, Supervielle Jeanne, Chemouny Jonathan M, Dardier Virginie, Lacroix Agnes, Dion Ludivine, Vigneau Cécile
University of Rennes, CHU Rennes, INSERM, EHESP, IRSET (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000, Rennes, France.
Laboratoire de psychologie, comportement, cognition et communication (LP3 C), Université Rennes-Rennes 2, Rennes, France.
Clin Kidney J. 2021 Mar 3;14(8):1871-1878. doi: 10.1093/ckj/sfab049. eCollection 2021 Aug.
Although pregnancy remains exceptional in women after heart, liver or lung transplant, obstetricians and nephrologists are regularly confronted with pregnancy in renal transplant recipients. National and international registries have described the epidemiology of maternal, foetal and neonatal complications, and transplantation societies have published recommendations on the monitoring of these high-risk pregnancies. In this review, we summarize the existing data on maternal and foetal complications of pregnancies in women after renal transplant, especially the management of immunosuppression. We also describe the few available data on the middle- and long-term outcomes of their children who were exposed to immunosuppressive drugs.
尽管心脏、肝脏或肺移植后的女性怀孕情况仍属罕见，但产科医生和肾病科医生经常会遇到肾移植受者怀孕的情况。国家和国际登记处已经描述了孕产妇、胎儿和新生儿并发症的流行病学情况，移植协会也发布了关于监测这些高危妊娠的建议。在本综述中，我们总结了肾移植后女性怀孕的孕产妇和胎儿并发症的现有数据，尤其是免疫抑制的管理。我们还描述了关于其接触免疫抑制药物的子女的中长期结局的少量可用数据。
