一例免疫功能正常宿主中与新型冠状病毒肺炎相关的自身免疫性溶血性贫血伴高铁蛋白血症病例
A Case of COVID-19-Associated Autoimmune Hemolytic Anemia With Hyperferritinemia in an Immunocompetent Host.
作者信息
Huda Zoha, Jahangir Abdullah, Sahra Syeda, Rafay Khan Niazi Muhammad, Anwar Shamsuddin, Glaser Allison, Jahangir Ahmad
机构信息
Medicine, The City University of New York (CUNY) School of Medicine, New York, USA.
Internal Medicine, Staten Island University Hospital, Northwell Health, New York, USA.
出版信息
Cureus. 2021 Jun 30;13(6):e16078. doi: 10.7759/cureus.16078. eCollection 2021 Jun.
We report an interesting case of a middle-aged gentleman who presented with diabetic ketoacidosis (DKA) and tested polymerase chain reaction (PCR) positive for COVID-19 infection. His hospital stay was complicated by acute kidney injury, hematuria, and normocytic anemia. Initial chest x-ray demonstrated bibasilar opacities. D-dimer and C-reactive protein were elevated. During his hospital stay, his hemoglobin decreased from 13.4 g/dL to 9 g/dL, and further workup demonstrated ferritin of 49,081 ng/mL with lactate dehydrogenase of 1665 U/L. He was treated with prednisone and folic acid for autoimmune hemolytic anemia (AIHA). Ferritin was downtrended, and hemoglobin stabilized. As demonstrated by this case report and prior literature review, COVID-19 infection can be associated with AIHA.
我们报告了一例有趣的病例，一名中年男性患者出现糖尿病酮症酸中毒（DKA），并经聚合酶链反应（PCR）检测确诊为新型冠状病毒肺炎（COVID-19）感染阳性。他住院期间并发急性肾损伤、血尿和正细胞性贫血。最初的胸部X光显示双肺底有模糊影。D-二聚体和C反应蛋白升高。在住院期间，他的血红蛋白从13.4 g/dL降至9 g/dL，进一步检查显示铁蛋白为49,081 ng/mL，乳酸脱氢酶为1665 U/L。他因自身免疫性溶血性贫血（AIHA）接受了泼尼松和叶酸治疗。铁蛋白下降，血红蛋白稳定。正如本病例报告和先前文献综述所示，COVID-19感染可能与AIHA有关。
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