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[过氧乙酸作用下细菌和芽孢的亚显微研究及其作用机制的各个方面]

[Submicroscopic study of bacteria and spores under the effect of peracetic acid and various aspects of the mechanism of its action].

作者信息

Pavlova I B, Kulikovskiĭ A V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Jan(1):37-41.

PMID:343456
Abstract

Microbial cells (E. coli and staphylococcus) and B. cereus spores were used in this work. Peracetic acid in a concentration of 0.005% caused the death of 99% of the microbes in 20 minutes, and 0.1% peracetic acid caused the death of 99% of the spores in 45 minutes. Changes in the surface and internal structures of the cells were revealed on the ultrathin sections of microbial cells and spores after the action of the preparation. The noted changes were explained by disturbance of permeability barrier and a high reactogenic capacity of the activated oxygen of peracetic acid.

摘要

本研究使用了微生物细胞(大肠杆菌和葡萄球菌)以及蜡样芽孢杆菌孢子。浓度为0.005%的过氧乙酸在20分钟内可使99%的微生物死亡,而0.1%的过氧乙酸在45分钟内可使99%的孢子死亡。制剂作用后,在微生物细胞和孢子的超薄切片上观察到细胞表面和内部结构的变化。上述变化可归因于通透性屏障的破坏以及过氧乙酸活性氧的高反应活性。

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