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犬支原体在中枢神经系统向人类的传播。

Canine-to-Human Transmission of Mycoplasma canis in the Central Nervous System.

机构信息

College of Osteopathic Medicine of the Pacific Western University of Health Sciences, Pomona, California, USA.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, USA.

出版信息

J Pediatric Infect Dis Soc. 2022 Jan 27;11(1):28-30. doi: 10.1093/jpids/piab049.

Abstract

Dog bites remain a common occurrence in our society, particularly in toddlers and small children under the age of 2. Injuries to the head and face, more common in younger children, can often lead to significant morbidity. Additionally, there continues to be considerable clinical equipoise for standardized post-dog bite injury management. Here, we present the only reported pediatric case in the literature of Mycoplasma canis-associated central nervous system (CNS) infection in an 11-month-old infant who sustained a dog bite to the calvarium. The prevalence of dog bites during the SARS-CoV-2 pandemic had interestingly tripled in number after stay-at-home orders in 1 particular pediatric emergency department in Colorado. This observation paired with advances in microbiological identification like MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight mass spectrometer) may lead to the identification of future cases of uniquely canine pathogens that play a role in human infection.

摘要

狗咬伤在我们的社会中仍然很常见,特别是在 2 岁以下的幼儿和儿童中。头部和面部受伤更为常见,通常会导致严重的发病率。此外,对于标准化的狗咬伤后处理,仍然存在相当大的临床均衡性。在这里,我们报告了文献中唯一报道的小儿病例,即患有犬支原体相关中枢神经系统 (CNS) 感染的 11 个月大婴儿,该婴儿的颅骨被狗咬伤。有趣的是,在科罗拉多州的一家儿科急诊室发布居家令后,SARS-CoV-2 大流行期间狗咬伤的数量增加了两倍。这种观察结果与 MALDI-TOF(基质辅助激光解吸/电离飞行时间质谱仪)等微生物鉴定技术的进步相结合,可能会发现未来的独特犬病原体病例,这些病原体在人类感染中起作用。

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