Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.
mSphere. 2021 Aug 25;6(4):e0045021. doi: 10.1128/mSphere.00450-21. Epub 2021 Aug 4.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity was assessed for 3,066 individuals visiting hospitals in St. Louis, Missouri, during July 2020, November 2020, or January 2021. Seropositivity in children increased from 5.22% in July to 21.16% in January. In the same time frame, seropositivity among adults increased from 4.52% to 19.03%, prior to initiation of mass vaccination. This study determined the percentage of children and adult samples from the St. Louis metropolitan area in Missouri with SARS-CoV-2 antibodies during three collection periods spanning July 2020 to January 2021. By January 2021, 20.68% of the tested individuals had antibodies. These results show the evolution of the SARS-CoV-2 pandemic in St. Louis, Missouri, and provide a snapshot of the extent of infection just prior to the start of mass vaccination.
我们评估了 2020 年 7 月、11 月或 2021 年 1 月期间访问密苏里州圣路易斯市医院的 3066 个人的严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）血清阳性率。儿童的血清阳性率从 7 月的 5.22%增加到 1 月的 21.16%。在同一时间范围内，成年人的血清阳性率从 4.52%增加到 19.03%，在此之前已经开始大规模接种疫苗。本研究确定了密苏里州圣路易斯大都市区在 2020 年 7 月至 2021 年 1 月三个采集期间内具有 SARS-CoV-2 抗体的儿童和成人样本的百分比。到 2021 年 1 月，20.68%的检测个体具有抗体。这些结果显示了 SARS-CoV-2 在密苏里州圣路易斯市的流行情况的演变，并提供了大规模接种疫苗前感染程度的快照。
