Faculty of Social Sciences, School of Psychology, University of Ottawa, Ottawa, Canada.
Ottawa Hospital Research Institute, Ottawa, Canada.
PLoS One. 2021 Aug 4;16(8):e0255538. doi: 10.1371/journal.pone.0255538. eCollection 2021.
This study investigated the association between post-stroke fatigue and inability to return to work/drive in young patients aged <60 years with first stroke who were employed prior to infarct while controlling for stroke severity, age, extent of disability, cognitive function, and depression. The Fatigue Severity Scale (FSS) was used to evaluate post-stroke fatigue in this 1-year prospective cohort study. Follow-ups were completed at 3, 6, and 12 months post rehabilitation discharge. A total of 112 patients were recruited, 7 were excluded, due to loss to follow-up (n = 6) and being palliative (n = 1), resulting in 105 participants (71% male, average age 49 ±10.63 years). Stroke patients receiving both inpatient and outpatient rehabilitation were consecutively recruited. Persistent fatigue remained associated with inability to return to work when controlling for other factors at 3 months (adjusted OR = 18, 95% CI: 2.9, 110.3, p = 0.002), 6 months (adjusted OR = 29.81, 95% CI: 1.7, 532.8, p = 0.021), and 12 months (adjusted OR = 31.6, 95% CI: 1.8, 545.0, p = 0.018). No association was found between persistent fatigue and return to driving. Fatigue at admission was associated with inability to return to work at 3 months but not return to drive. Persistent fatigue was found to be associated with inability to resume work but not driving. It may be beneficial to routinely screen post-stroke fatigue in rehabilitation and educate stroke survivors and employers on the impacts of post-stroke fatigue on return to work.
这项研究调查了在梗死前就业的年龄<60 岁的首次卒中年轻患者中，卒中后疲劳与无法重返工作/驾驶之间的关系，同时控制了卒中严重程度、年龄、残疾程度、认知功能和抑郁。在这项为期 1 年的前瞻性队列研究中，使用疲劳严重程度量表（FSS）评估卒中后疲劳。在康复出院后 3、6 和 12 个月进行随访。共招募了 112 名患者，7 名因失访（n=6）和姑息治疗（n=1）而被排除，最终有 105 名参与者（71%为男性，平均年龄 49±10.63 岁）。连续招募接受住院和门诊康复治疗的卒中患者。在控制其他因素后，3 个月（调整后的 OR=18，95%CI：2.9，110.3，p=0.002）、6 个月（调整后的 OR=29.81，95%CI：1.7，532.8，p=0.021）和 12 个月（调整后的 OR=31.6，95%CI：1.8，545.0，p=0.018）时，持续疲劳仍与无法重返工作相关。持续疲劳与无法恢复驾驶之间没有关联。入院时的疲劳与 3 个月时无法重返工作相关，但与无法恢复驾驶无关。持续疲劳与无法恢复工作相关，但与无法恢复驾驶无关。在康复过程中常规筛查卒中后疲劳，并向卒中幸存者和雇主教育卒中后疲劳对重返工作的影响，可能会有所帮助。
