一种用于表征生物合成人生长激素的反相高效液相色谱法。
A reversed-phase high-performance liquid chromatographic method for characterization of biosynthetic human growth hormone.
作者信息
Riggin R M, Dorulla G K, Miner D J
机构信息
Bioanalytical Development Department, Eli Lilly and Company, Indianapolis, Indiana 46285.
出版信息
Anal Biochem. 1987 Nov 15;167(1):199-209. doi: 10.1016/0003-2697(87)90152-7.
PMID:3434796
Abstract
An isocratic reversed-phase high-performance liquid chromatographic method for the determination of human growth hormone (HGH) purity is described. This method offers superior resolution of HGH-related substances (e.g., sulfoxide and desamido derivatives) from unmodified HGH when compared to a number of alternative chromatographic and electrophoretic techniques.
摘要
描述了一种用于测定人生长激素（HGH）纯度的等度反相高效液相色谱法。与许多其他色谱和电泳技术相比，该方法能从未修饰的HGH中更好地分离出HGH相关物质（如亚砜和脱酰胺衍生物）。
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