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一种用于表征生物合成人生长激素的反相高效液相色谱法。

A reversed-phase high-performance liquid chromatographic method for characterization of biosynthetic human growth hormone.

作者信息

Riggin R M, Dorulla G K, Miner D J

机构信息

Bioanalytical Development Department, Eli Lilly and Company, Indianapolis, Indiana 46285.

出版信息

Anal Biochem. 1987 Nov 15;167(1):199-209. doi: 10.1016/0003-2697(87)90152-7.

DOI:10.1016/0003-2697(87)90152-7
PMID:3434796
Abstract

An isocratic reversed-phase high-performance liquid chromatographic method for the determination of human growth hormone (HGH) purity is described. This method offers superior resolution of HGH-related substances (e.g., sulfoxide and desamido derivatives) from unmodified HGH when compared to a number of alternative chromatographic and electrophoretic techniques.

摘要

描述了一种用于测定人生长激素(HGH)纯度的等度反相高效液相色谱法。与许多其他色谱和电泳技术相比,该方法能从未修饰的HGH中更好地分离出HGH相关物质(如亚砜和脱酰胺衍生物)。

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A reversed-phase high-performance liquid chromatographic method for characterization of biosynthetic human growth hormone.一种用于表征生物合成人生长激素的反相高效液相色谱法。
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