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癌症患者相关疲劳及伴随睡眠障碍的特征。

Characteristics of Cancer-Related Fatigue and Concomitant Sleep Disturbance in Cancer Patients.

机构信息

Departments of Health Disparities Research, University of Texas MD Anderson Cancer Center (I.H.C.W.), Houston, TX, USA.

Departments of Pulmonary Medicine, University of Texas MD Anderson Cancer Center (D.D.B., S.A.F., L.B.), Houston, TX, USA.

出版信息

J Pain Symptom Manage. 2022 Jan;63(1):e1-e8. doi: 10.1016/j.jpainsymman.2021.07.025. Epub 2021 Aug 1.

Abstract

CONTEXT

Cancer patients often experience cancer-related fatigue (CRF) and sleep disturbances due to cancer and cancer treatment, and symptoms can persist long after treatment. Despite these common occurrences, few studies simultaneously characterize CRF and sleep architecture among cancer patients.

OBJECTIVES

The objective was to characterize CRF and the sleep architecture of patients seen in a CRF clinic and sleep clinic at the University of Texas MD Anderson Cancer Center.

METHODS

CRF Clinic medical records were retrospectively reviewed from September 1, 2006, to September 30, 2010, for self-reported performance status, fatigue, pain, sleep disturbance, depression, anxiety, and sleepiness (n = 219). Polysomnography results were recorded for those referred for additional sleep consultation (n = 39).

RESULTS

Notably, patients often reported fatigue, sleep disturbance, excessive daytime sleepiness, and a majority of patients referred for a sleep consultation were diagnosed with obstructive sleep apnea (n = 33).

CONCLUSION

The results highlight the promise of an interdisciplinary collaboration between dedicated a CRF clinic and sleep clinic to conduct effective assessments to identify treatable CRF and sleep disorders.

摘要

背景

癌症患者由于癌症及其治疗常常会经历癌因性疲乏(CRF)和睡眠障碍,且这些症状在治疗结束后很长时间内仍会持续存在。尽管这些情况很常见,但很少有研究同时描述癌症患者的 CRF 和睡眠结构。

目的

旨在描述在德克萨斯大学 MD 安德森癌症中心的 CRF 诊所和睡眠诊所就诊的患者的 CRF 和睡眠结构。

方法

回顾性分析 2006 年 9 月 1 日至 2010 年 9 月 30 日 CRF 诊所的医疗记录,以了解患者的自我报告的表现状态、疲乏、疼痛、睡眠障碍、抑郁、焦虑和嗜睡(n=219)。对于那些被转介进行额外睡眠咨询的患者(n=39),记录了多导睡眠图的结果。

结果

值得注意的是,患者经常报告疲劳、睡眠障碍、白天过度嗜睡,并且大多数被转介进行睡眠咨询的患者被诊断为阻塞性睡眠呼吸暂停(n=33)。

结论

这些结果突出了专门的 CRF 诊所和睡眠诊所之间开展跨学科合作的潜力,以便进行有效的评估,以确定可治疗的 CRF 和睡眠障碍。

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