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70岁以上患者同期双侧全膝关节置换术后的围手术期并发症

Perioperative Complications in Patients over 70 Years of Age following Simultaneous Bilateral Total Knee Arthroplasty.

作者信息

Kozai Landon, Matsumoto Maya, Mathews Kristin, Andrews Samantha, Nakasone Cass

机构信息

John A. Burns School of Medicine, Honolulu, Hawaii.

Straub Medical Center, Bone and Joint Center, Honolulu, Hawaii.

出版信息

J Knee Surg. 2023 Mar;36(4):362-367. doi: 10.1055/s-0041-1733884. Epub 2021 Aug 4.

Abstract

Single-stage bilateral total knee arthroplasty (ssBTKA) can be used for patients presenting with bilateral arthritis and may result in fewer systemic and wound complications compared with two, independent procedures. However, the safety of ssBTKA in the elderly remains controversial. Therefore, the purpose of this study was to compare early complications and transfusion rates following ssBTKA in patients ≤ 70 years old or > 70 years old. This retrospective chart review of 313 consecutive patients undergoing ssBTKA included 174 patients ≤ 70 years old and 139 patients > 70 years old. Perioperative variables and postoperative complications were compared with univariate analyses between age groups. Multivariate analyses were performed to determine risk factors for developing perioperative complications and transfusions. Compared with patients ≤ 70, patients > 70 had significantly lower body mass index ( < 0.001) and were more commonly female ( = 0.024). Although wound ( > 0.12) and systemic complications ( > 0.54) were similar, 23% of patients > 70 required transfusion compared with only 8% of patients ≤ 70 ( < 0.001). Patients with preoperative anemia ( < 0.001), age > 70 ( = 0.002), or diabetes mellitus ( = 0.007) were at 5.7, 3.3, and 2.9 times greater risk for requiring a transfusion, respectively. Patients > 70 undergoing ssBTKA have a similar complication profile to patients ≤ 70 years old, suggesting age should not be an absolute exclusion criterion for ssBTKA. However, the risk of transfusion was significantly higher in those > 70, despite lower tourniquet times. Treatment of preoperative anemia may decrease the risk of transfusion and could provide adequate safety for patients > 70 to undergo ssBTKA by an experienced surgeon.

摘要

单阶段双侧全膝关节置换术(ssBTKA)可用于双侧关节炎患者,与两次独立手术相比,可能会减少全身和伤口并发症。然而,ssBTKA在老年人中的安全性仍存在争议。因此,本研究的目的是比较70岁及以下或70岁以上患者行ssBTKA后的早期并发症和输血率。这项对313例连续接受ssBTKA患者的回顾性病历审查包括174例70岁及以下患者和139例70岁以上患者。对年龄组之间的围手术期变量和术后并发症进行单因素分析比较。进行多因素分析以确定发生围手术期并发症和输血的危险因素。与70岁及以下患者相比,70岁以上患者的体重指数显著更低(<0.001),且女性更为常见(=0.024)。虽然伤口(>0.12)和全身并发症(>0.54)相似,但70岁以上患者中有23%需要输血,而70岁及以下患者中只有8%需要输血(<0.001)。术前贫血(<0.001)、年龄>70岁(=0.002)或糖尿病(=0.007)的患者需要输血的风险分别高5.7倍、3.3倍和2.9倍。70岁以上行ssBTKA的患者与70岁及以下患者的并发症情况相似,这表明年龄不应成为ssBTKA的绝对排除标准。然而,70岁以上患者的输血风险显著更高,尽管止血带使用时间更短。术前贫血的治疗可能会降低输血风险,并可为经验丰富外科医生为70岁以上患者行ssBTKA提供足够的安全性。

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