Department of Cardiovascular Surgery, Sapporo Medical University School of Medicine, 291, Minami 1-jo Nishi 16-chome Chuo-ku, Sapporo, 060-8543, Japan.
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
J Cardiothorac Surg. 2021 Aug 4;16(1):219. doi: 10.1186/s13019-021-01598-5.
There are a lot of reports of the renal failure and heart failure due to coarctation of the aorta. However, there are no case reports in which revascularization dramatically improved left ventricular function in patients with progressive decline in left ventricular function. Herein, we present a rare case in which the left ventricular function was dramatically improved by surgical treatment for progressive left ventricular dysfunction due to atypical coarctation of the aorta.
A 58-year-old man underwent left axillary artery-bilateral femoral artery bypass at another hospital for atypical coarctation of the aorta due to Takayasu's arteritis. Approximately 10 years later, he was re-hospitalized for heart failure, and the left ventricular ejection fraction gradually decreased to 28%. Computed tomography showed severe calcification and stenosis at the same site from the peripheral thoracic descending aorta to the lower abdominal aorta of the renal artery, and aortography showed delayed bilateral renal artery blood flow. An increase in plasma renin activity was also observed. Despite the administration of multiple antihypertensive drugs, blood pressure control was insufficient. We decided to perform surgical treatment to improve progressive cardiac dysfunction due to increased afterload and activated plasma renin activity. Descending thoracic aorta-abdominal aorta bypass and revascularization of the bilateral renal arteries via the great saphenous vein grafts were performed. Postoperative blood pressure control was improved, and the dose of antihypertensive drugs could be reduced. Plasma renin activity decreased, and transthoracic echocardiography 1.5 years later showed an improvement in contractility with a left ventricular ejection fraction of 58%.
In atypical coarctation of the aorta in patients with decreased bilateral renal blood flow, heart failure due to renal hypertension, and progressive decrease in left ventricular contractility, descending thoracic aorta-abdominal aortic bypass and bilateral renal artery recirculation can be extremely effective.
由于主动脉缩窄,有很多关于肾衰竭和心力衰竭的报道。然而,对于由于非典型主动脉缩窄导致左心室功能进行性下降的患者,血管重建术显著改善左心室功能的病例报告尚不多见。在此,我们报告了一例罕见病例,由于非典型主动脉缩窄,左心室功能进行性下降,手术治疗显著改善了左心室功能。
一名 58 岁男性因 Takayasu 动脉炎导致的非典型主动脉缩窄,在另一家医院行左腋动脉-双侧股动脉旁路术。大约 10 年后,他因心力衰竭再次住院,左心室射血分数逐渐降至 28%。计算机断层扫描显示从外周胸降主动脉到肾动脉下腹部主动脉同一部位严重钙化和狭窄,主动脉造影显示双侧肾动脉血流延迟。还观察到血浆肾素活性增加。尽管使用了多种降压药物,但血压控制仍不理想。我们决定进行手术治疗,以改善因后负荷增加和激活的血浆肾素活性导致的进行性心脏功能障碍。行降主动脉-腹主动脉旁路术,并通过大隐静脉移植物重建双侧肾动脉血运。术后血压控制得到改善,降压药物剂量得以减少。血浆肾素活性下降,1.5 年后经胸超声心动图显示收缩功能改善,左心室射血分数为 58%。
对于双侧肾血流量减少、肾性高血压性心力衰竭和左心室收缩力进行性下降的非典型主动脉缩窄患者,降主动脉-腹主动脉旁路术和双侧肾动脉再循环术可能非常有效。