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尺骨近端肿瘤切除术后的肘关节重建:挑战与解决方案。

Elbow reconstruction after excision of proximal ulna tumors: Challenges and solutions.

作者信息

Gulia Ashish, Pruthi Manish, Gupta Srinath, Nadkarni Shravan

机构信息

Dept of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Mumbai, India.

Assistant Professor, Bone and Soft Tissue Services, Dept of Surgical Oncology, Tata Memorial Hospital, and Homi Bhabha National Institute (HBNI), Mumbai, India.

出版信息

J Clin Orthop Trauma. 2021 Jul 6;20:101496. doi: 10.1016/j.jcot.2021.101496. eCollection 2021 Sep.

DOI:10.1016/j.jcot.2021.101496
PMID:34350096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8319519/
Abstract

Most malignant bone tumors are treated with surgical excision, adhering to oncologic principles, followed by reconstruction to preserve form and function whenever feasible. Primary bone tumors around the elbow are rare accounting for <1% of all skeletal tumors. They pose a reconstructive challenge, due to the complex interplay between the osseous & capsulo-ligamentous structures which is essential for elbow stability and function. Tumors affecting the proximal ulna are rare and reconstruction of the defects following these tumors is extremely challenging. Various reconstruction options like arthrodesis, autogenous bone grafts, allografts, re-implantation of sterilized tumor bone, pseudoarthrosis, and endoprosthesis have been tried with variable success. However, due to lack of standardization and the rarity of the site, surgeons are often in a dilemma to choose the correct option. This can lead to suboptimal functional outcomes and long-term failures. In this article, we reviewed the published literature on proximal ulnar tumors and noted the pros and cons of various reconstructive procedures. We have also attempted to formulate reconstruction recommendations based on the level of resection of proximal ulna.

摘要

大多数恶性骨肿瘤采用手术切除治疗,遵循肿瘤学原则,只要可行,术后进行重建以保留外形和功能。肘部周围的原发性骨肿瘤罕见,占所有骨骼肿瘤的比例不到1%。由于对维持肘关节稳定性和功能至关重要的骨结构与关节囊韧带结构之间存在复杂的相互作用,这些肿瘤带来了重建方面的挑战。影响尺骨近端的肿瘤罕见,对这些肿瘤切除后的缺损进行重建极具挑战性。已经尝试了各种重建方法,如关节融合术、自体骨移植、同种异体骨移植、灭菌肿瘤骨再植入、假关节形成和假体植入,但效果不一。然而,由于缺乏标准化以及该部位的罕见性,外科医生在选择正确的重建方法时常常左右为难。这可能导致功能结果不理想和长期失败。在本文中,我们回顾了关于尺骨近端肿瘤的已发表文献,并指出了各种重建手术的优缺点。我们还试图根据尺骨近端的切除水平制定重建建议。

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Elbow reconstruction after excision of proximal ulna tumors: Challenges and solutions.尺骨近端肿瘤切除术后的肘关节重建:挑战与解决方案。
J Clin Orthop Trauma. 2021 Jul 6;20:101496. doi: 10.1016/j.jcot.2021.101496. eCollection 2021 Sep.
2
Do irradiated osteo-articular recycled tumor autografts still hold promise for biological joint reconstruction? Our experience with acetabular and proximal ulna ECRT.经过辐照的骨-关节自体回收肿瘤移植物在生物性关节重建方面仍有前景吗?我们在髋臼和尺骨近端进行扩大切除再植术的经验。
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引用本文的文献

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Curr Oncol. 2025 Jul 22;32(8):411. doi: 10.3390/curroncol32080411.
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Outcomes of osteoarticular ulna allograft for the reconstruction of proximal ulna tumour.同种异体骨关节尺骨移植重建尺骨近端肿瘤的疗效
Bone Jt Open. 2024 Sep 12;5(9):749-757. doi: 10.1302/2633-1462.59.BJO-2024-0088.R1.
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Outcomes of management of primary benign aggressive or malignant bone tumors around the elbow by limb-salvage surgery.采用保肢手术治疗肘部周围原发性良性侵袭性或恶性骨肿瘤的疗效
J Exp Orthop. 2023 Oct 23;10(1):105. doi: 10.1186/s40634-023-00675-z.
4
Elbow hemiarthroplasty with a 3D-printed prosthesis for distal humeral bone defects after tumor excision: a case report.采用3D打印假体行肘关节半关节成形术治疗肿瘤切除术后肱骨远端骨缺损:1例病例报告
3D Print Med. 2023 Jun 14;9(1):18. doi: 10.1186/s41205-023-00178-8.

本文引用的文献

1
Clinical Outcomes of Osteoarticular Extracorporeal Irradiated Autograft for Malignant Bone Tumor.骨关节体外照射自体骨移植治疗恶性骨肿瘤的临床疗效
Sarcoma. 2020 Mar 30;2020:9672093. doi: 10.1155/2020/9672093. eCollection 2020.
2
Radial Neck-to-Humerus Transposition for Elbow Reconstruction Following Oncologic Resection of the Proximal Ulna: A Report of Two Cases.尺骨近端肿瘤切除术后肘关节重建的桡骨颈至肱骨转位术:两例报告
JBJS Case Connect. 2019 Dec;9(4):e0451. doi: 10.2106/JBJS.CC.18.00451.
3
Reconstructive Challenges of Proximal Ulnar Bone Tumors: Our Experience with Biological Osteoarticular Reconstruction Using Extracorporeal Irradiation and Reimplantation.尺骨近端骨肿瘤的重建挑战:我们应用体外照射和再植入进行生物性骨关节重建的经验。
Sarcoma. 2019 Apr 11;2019:7812018. doi: 10.1155/2019/7812018. eCollection 2019.
4
Ulnohumeral reconstruction with autogenous, nonvascularized, fibular graft for metastatic clear cell renal carcinoma of the proximal ulna: a case report.采用自体非血管化腓骨移植进行尺骨近端转移性透明细胞肾细胞癌的尺肱重建:一例报告
JSES Open Access. 2017 Jul 24;1(2):90-93. doi: 10.1016/j.jses.2017.06.002. eCollection 2017 Jun.
5
Elbow Reconstruction Following an Extensive Resection of the Proximal Part of the Ulna in a Patient with Ewing Sarcoma: A Case Report.
JBJS Case Connect. 2013 Nov 13;3(4 Suppl 3):e111. doi: 10.2106/JBJS.CC.L.00003.
6
The application of 3D printed surgical guides in resection and reconstruction of malignant bone tumor.3D打印手术导板在恶性骨肿瘤切除与重建中的应用
Oncol Lett. 2017 Oct;14(4):4581-4584. doi: 10.3892/ol.2017.6749. Epub 2017 Aug 11.
7
Rare Giant Cell Tumor of Olecranon Bone!!!!罕见的尺骨鹰嘴巨细胞瘤!!!!
J Orthop Case Rep. 2016 Sep-Oct;6(4):27-30. doi: 10.13107/jocr.2250-0685.556.
8
Reconstruction of the elbow and forearm for Ewing sarcoma of ulna: A new biological technique.尺骨尤因肉瘤的肘和前臂重建:一种新的生物技术。
Int J Shoulder Surg. 2016 Apr-Jun;10(2):85-8. doi: 10.4103/0973-6042.180721.
9
Ewing's sarcoma of the ulna treated with sub-total resection and reconstruction using a non-vascularized, autogenous fibular graft and hernia mesh: A case report.采用非血管化自体腓骨移植和疝修补网进行次全切除和重建治疗尺骨尤因肉瘤:一例报告
Oncol Lett. 2015 Oct;10(4):2067-2070. doi: 10.3892/ol.2015.3534. Epub 2015 Jul 24.
10
Reconstruction of Elbow by Free Fibular Graft in a Case of Osteoclastoma of Proximal Ulna: A Rare Case Report.游离腓骨移植重建尺骨近端骨巨细胞瘤患者的肘关节:1例罕见病例报告
Case Rep Med. 2015;2015:429309. doi: 10.1155/2015/429309. Epub 2015 Aug 12.