Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Dig Endosc. 2022 Jan;34(2):284-296. doi: 10.1111/den.14102. Epub 2021 Aug 27.
An accumulating body of evidence has shown that detection and resection of pre-cancerous adenoma by colonoscopy could effectively prevent colorectal cancer (CRC) and its related mortality. Among various colonoscopy quality indicators, such as cecal intubation rate, withdrawal time, and adenoma detection rate (ADR); ADR is the most important and most closely associated with the subsequent risk of CRC. Image-enhanced endoscopy (IEE), including digital and dye-based IEE, was originally developed to discriminate neoplastic from non-neoplastic lesions but later studies have demonstrated that it can also enhance lesion detection by enhancing the contrast between the lesion and background colonic mucosa. Nevertheless, using IEE in colonoscopy for lesion detection is still not the standard way of practice in the real world. For a better understanding of current IEE modalities, this review introduces and compares the currently available IEE modalities and their efficacy in detecting adenoma from the results of randomized controlled trials or meta-analyses.
越来越多的证据表明，通过结肠镜检查发现并切除癌前腺瘤，可以有效地预防结直肠癌（CRC）及其相关死亡率。在各种结肠镜检查质量指标中，如盲肠插管率、退镜时间和腺瘤检出率（ADR）；ADR 是最重要的，与 CRC 的后续风险最密切相关。增强内镜（IEE），包括数字和基于染料的 IEE，最初是为了区分肿瘤性和非肿瘤性病变而开发的，但后来的研究表明，它还可以通过增强病变与背景结肠黏膜之间的对比度来增强病变的检测。然而，在结肠镜检查中使用 IEE 进行病变检测在现实世界中仍然不是标准做法。为了更好地了解当前的 IEE 方式，本综述介绍并比较了目前可用的 IEE 方式及其在随机对照试验或荟萃分析结果中检测腺瘤的效果。
