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1
Cloning and characterization of tetM gene from a Ureaplasma urealyticum strain.解脲脲原体菌株tetM基因的克隆与鉴定
Antimicrob Agents Chemother. 1987 Nov;31(11):1852-4. doi: 10.1128/AAC.31.11.1852.
2
Detection of tetracycline-resistant strains of Ureaplasma urealyticum by hybridization assays.通过杂交试验检测解脲脲原体的四环素耐药菌株。
Eur J Clin Microbiol Infect Dis. 1989 Jul;8(7):636-8. doi: 10.1007/BF01968147.
3
Characterization of tetracycline-resistant strains of Ureaplasma urealyticum.解脲脲原体四环素耐药菌株的特性分析
J Antimicrob Chemother. 1988 Mar;21(3):319-32. doi: 10.1093/jac/21.3.319.
4
TetM tetracycline-resistant determinants in Ureaplasma urealyticum.解脲脲原体中的四环素抗性决定因子TetM
Pediatr Infect Dis. 1986 Nov-Dec;5(6 Suppl):S338-40. doi: 10.1097/00006454-198611010-00032.
5
Dissemination of the tetM tetracycline resistance determinant to Ureaplasma urealyticum.四环素抗性决定子tetM向解脲脲原体的传播。
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Cloning of Ureaplasma urealyticum DNA sequences showing genetic homology with urease genes from gram-negative bacteria.
Res Microbiol. 1989 May-Jun;140(4-5):281-90. doi: 10.1016/0923-2508(89)90020-x.
7
Rapid detection of tetM in Mycoplasma hominis and Ureaplasma urealyticum by PCR: tetM confers resistance to tetracycline but not necessarily to doxycycline.通过聚合酶链反应（PCR）快速检测人型支原体和解脲脲原体中的tetM基因：tetM基因赋予对四环素的耐药性，但不一定赋予对多西环素的耐药性。
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The nucleotide sequence of the tetracycline resistance determinant tetM from Ureaplasma urealyticum.解脲脲原体中四环素抗性决定因子tetM的核苷酸序列。
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Detection of the tetM resistance determinant among phenotypically sensitive Ureaplasma species by a novel real-time PCR method.通过一种新型实时聚合酶链反应方法检测表型敏感脲原体属物种中的tetM耐药决定簇。
Diagn Microbiol Infect Dis. 2015 Feb;81(2):85-8. doi: 10.1016/j.diagmicrobio.2014.10.013. Epub 2014 Nov 5.

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1
Resistance to tetracycline, macrolide-lincosamide-streptogramin, trimethoprim, and sulfonamide drug classes.对四环素、大环内酯-林可酰胺-链阳菌素、甲氧苄啶和磺胺类药物的耐药性。
Mol Biotechnol. 2002 Mar;20(3):261-83. doi: 10.1385/MB:20:3:261.
2
Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance.四环素类抗生素：作用机制、应用、分子生物学及细菌耐药性流行病学
Microbiol Mol Biol Rev. 2001 Jun;65(2):232-60 ; second page, table of contents. doi: 10.1128/MMBR.65.2.232-260.2001.
3
Detection of tetracycline resistance determinants in pig isolates from three herds with different histories of antimicrobial agent exposure.对来自三个有不同抗菌剂接触史猪群的分离株中四环素抗性决定因素的检测。
Appl Environ Microbiol. 1993 May;59(5):1467-72. doi: 10.1128/aem.59.5.1467-1472.1993.
4
Genetic basis of tetracycline resistance in food-borne isolates of Listeria innocua.无害李斯特菌食源分离株中四环素抗性的遗传基础。
Appl Environ Microbiol. 1993 Feb;59(2):614-6. doi: 10.1128/aem.59.2.614-616.1993.
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Tetracycline resistance and TetM in oral anaerobic bacteria and Neisseria perflava-N. sicca.口腔厌氧菌及微黄奈瑟菌-干燥奈瑟菌中的四环素耐药性与TetM
Antimicrob Agents Chemother. 1988 Aug;32(8):1271-3. doi: 10.1128/AAC.32.8.1271.
6
Transfer of beta-lactamase plasmids from Neisseria gonorrhoeae to Neisseria meningitidis and commensal Neisseria species by the 25.2-megadalton conjugative plasmid.通过25.2兆道尔顿的接合性质粒将β-内酰胺酶质粒从淋病奈瑟菌转移至脑膜炎奈瑟菌和共生奈瑟菌属菌种。
Antimicrob Agents Chemother. 1988 Sep;32(9):1430-2. doi: 10.1128/AAC.32.9.1430.
7
High-level tetracycline resistance resulting from TetM in strains of Neisseria spp., Kingella denitrificans, and Eikenella corrodens.淋病奈瑟菌、反硝化金氏菌和腐蚀艾肯菌菌株中由TetM导致的高水平四环素耐药性。
Antimicrob Agents Chemother. 1988 May;32(5):765-7. doi: 10.1128/AAC.32.5.765.
8
Host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from Neisseria gonorrhoeae and related species.淋病奈瑟菌及相关物种中25.2兆达尔顿接合型四环素抗性质粒的宿主范围。
Antimicrob Agents Chemother. 1988 Apr;32(4):488-91. doi: 10.1128/AAC.32.4.488.
9
Plasmid-mediated Tet M in Haemophilus ducreyi.杜克雷嗜血杆菌中质粒介导的四环素抗性
Antimicrob Agents Chemother. 1989 Sep;33(9):1611-3. doi: 10.1128/AAC.33.9.1611.
10
Mechanisms of macrolide resistance in Ureaplasma urealyticum: a study on collection and clinical strains.解脲脲原体对大环内酯类抗生素耐药机制：收集菌株与临床菌株的研究
Eur J Epidemiol. 1989 Jun;5(2):146-53. doi: 10.1007/BF00156820.

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Identification of tetracycline-resistant R-plasmids in Streptococcus agalactiae (group B).无乳链球菌（B组）中四环素抗性R质粒的鉴定。
Antimicrob Agents Chemother. 1980 Nov;18(5):753-60. doi: 10.1128/AAC.18.5.753.
2
Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.大肠杆菌中由四种基因不同的四环素抗性决定簇编码的四环素主动外排
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Conjugative transfer of multiple antibiotic resistance markers in Streptococcus pneumoniae.肺炎链球菌中多种抗生素抗性标记的接合转移
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Heterogeneity of tetracycline resistance determinants.四环素抗性决定因素的异质性。
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Heterogeneity of tetracycline resistance determinants in Streptococcus.链球菌中四环素抗性决定因素的异质性
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Frequency of tetracycline resistance determinant classes among lactose-fermenting coliforms.乳糖发酵大肠菌群中四环素抗性决定簇类别的频率
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Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid.粪肠球菌中一种染色体携带的抗性转座子（Tn916）的证据，该转座子在没有接合质粒的情况下能够进行“接合”转移。
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解脲脲原体菌株tetM基因的克隆与鉴定

Cloning and characterization of tetM gene from a Ureaplasma urealyticum strain.

作者信息

Brown J T, Roberts M C

机构信息

Department of Pathobiology, University of Washington, Seattle 98177.

出版信息

Antimicrob Agents Chemother. 1987 Nov;31(11):1852-4. doi: 10.1128/AAC.31.11.1852.

DOI:10.1128/AAC.31.11.1852
PMID:3435130
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC175053/
Abstract

We have cloned a 4.9-kilobase (kb) HincII fragment which contains a tetracycline resistance determinant (tetM) from the chromosome of Ureaplasma urealyticum. The 4.9-kb HincII fragment contains DNA in addition to the structural gene, is closely related to the previously characterized 5.0-kb fragment from pJI3, and contains no normal ureaplasmal DNA sequences.

摘要

我们克隆了一个4.9千碱基（kb）的HincII片段，该片段含有来自解脲脲原体染色体的四环素抗性决定簇（tetM）。这个4.9 kb的HincII片段除了结构基因外还包含其他DNA，与之前鉴定的来自pJI3的5.0 kb片段密切相关，并且不包含正常的脲原体DNA序列。