淋病奈瑟菌及相关物种中25.2兆达尔顿接合型四环素抗性质粒的宿主范围。
Host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from Neisseria gonorrhoeae and related species.
作者信息
Roberts M C, Knapp J S
机构信息
Department of Pathobiology, University of Washington, Seattle 98195.
出版信息
Antimicrob Agents Chemother. 1988 Apr;32(4):488-91. doi: 10.1128/AAC.32.4.488.
Abstract
High-level tetracycline resistance in strains of Neisseria gonorrhoeae, Neisseria meningitidis, Kingella denitrificans, and Eikenella corrodens has recently been described. The resistance in each species is due to the acquisition of 25.2-megadalton conjugative plasmids that carry the tetracycline resistance determinant TetM. We examined the ability of commensal Neisseria species to serve as recipients in conjugation for these new plasmids. Most of the recipients (n = 21) tested had detectable conjugation frequencies (greater than 10(-9] with one or more of the donor strains. Transfer was not detected in Branhamella catarrhalis. Transconjugants were able to maintain the plasmids and act as donors in subsequent matings.
摘要
最近已报道淋病奈瑟菌、脑膜炎奈瑟菌、反硝化金氏菌和腐蚀艾肯菌菌株中存在高水平四环素耐药性。每个菌种中的耐药性是由于获得了携带四环素耐药决定簇TetM的25.2兆达尔顿接合质粒。我们检测了共生奈瑟菌属菌种作为这些新质粒接合受体的能力。所检测的大多数受体（n = 21）与一种或多种供体菌株的接合频率可检测到（大于10^(-9)）。在卡他布兰汉菌中未检测到转移。接合子能够维持质粒并在随后的交配中作为供体。
相似文献
1
Host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from Neisseria gonorrhoeae and related species.淋病奈瑟菌及相关物种中25.2兆达尔顿接合型四环素抗性质粒的宿主范围。
Antimicrob Agents Chemother. 1988 Apr;32(4):488-91. doi: 10.1128/AAC.32.4.488.
2
High-level tetracycline resistance resulting from TetM in strains of Neisseria spp., Kingella denitrificans, and Eikenella corrodens.淋病奈瑟菌、反硝化金氏菌和腐蚀艾肯菌菌株中由TetM导致的高水平四环素耐药性。
Antimicrob Agents Chemother. 1988 May;32(5):765-7. doi: 10.1128/AAC.32.5.765.
3
Transfer of beta-lactamase plasmids from Neisseria gonorrhoeae to Neisseria meningitidis and commensal Neisseria species by the 25.2-megadalton conjugative plasmid.通过25.2兆道尔顿的接合性质粒将β-内酰胺酶质粒从淋病奈瑟菌转移至脑膜炎奈瑟菌和共生奈瑟菌属菌种。
Antimicrob Agents Chemother. 1988 Sep;32(9):1430-2. doi: 10.1128/AAC.32.9.1430.
4
High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant.淋病奈瑟菌的高水平四环素耐药性是获得链球菌tetM决定簇的结果。
Antimicrob Agents Chemother. 1986 Nov;30(5):664-70. doi: 10.1128/AAC.30.5.664.
5
Conjugal transfer of beta-lactamase-producing plasmids of Neisseria gonorrhoeae to Neisseria meningitidis.淋病奈瑟菌产β-内酰胺酶质粒向脑膜炎奈瑟菌的接合转移
Microbiol Immunol. 1986;30(8):737-42. doi: 10.1111/j.1348-0421.1986.tb03000.x.
6
Conjugation of plasmids of Neisseria gonorrhoeae to other Neisseria species: potential reservoirs for the beta-lactamase plasmid.淋病奈瑟菌质粒与其他奈瑟菌属菌种的接合：β-内酰胺酶质粒的潜在储存库。
J Infect Dis. 1984 Sep;150(3):397-401. doi: 10.1093/infdis/150.3.397.
7
The 25.2 MDa tetracycline-resistance plasmid is not derived from the 24.5 MDa conjugative plasmid of Neisseria gonorrhoeae.这个25.2兆道尔顿的四环素抗性质粒并非源自淋病奈瑟菌的24.5兆道尔顿接合性质粒。
J Antimicrob Chemother. 1990 Jan;25(1):39-47. doi: 10.1093/jac/25.1.39.
8
Molecular evolution of tetracycline-resistance plasmids carrying TetM found in Neisseria gonorrhoeae from different countries.在来自不同国家的淋病奈瑟菌中发现的携带TetM的四环素抗性质粒的分子进化。
J Antimicrob Chemother. 1991 Aug;28(2):173-83. doi: 10.1093/jac/28.2.173.
9
Detection of the tetM determinant in Neisseria gonorrhoeae.淋病奈瑟菌中tetM决定簇的检测
Sex Transm Dis. 1993 Nov-Dec;20(6):329-33.
10
Plasmid analysis of Neisseria gonorrhoeae isolates and dissemination of tetM genes in southern Africa 1993-1995.1993 - 1995年非洲南部淋病奈瑟菌分离株的质粒分析及tetM基因的传播
J Antimicrob Chemother. 1997 Dec;40(6):817-22. doi: 10.1093/jac/40.6.817.
引用本文的文献
1
Revisiting the potential impact of doxycycline post-exposure prophylaxis on the selection of doxycycline resistance in Neisseria commensals.重新审视多西环素暴露后预防对共生奈瑟菌中多西环素耐药性选择的潜在影响。
Sci Rep. 2025 Apr 11;15(1):12400. doi: 10.1038/s41598-025-96244-8.
2
Re-visiting the potential impact of doxycycline post-exposure prophylaxis (doxy-PEP) on the selection of doxycycline resistance in commensals.重新审视强力霉素暴露后预防（强力霉素-PEP）对共生菌中强力霉素耐药性选择的潜在影响。
bioRxiv. 2025 Jan 9:2025.01.09.632169. doi: 10.1101/2025.01.09.632169.
3
Evolution and exchange of plasmids in pathogenic .在病原. 中质粒的进化和交换。
mSphere. 2023 Dec 20;8(6):e0044123. doi: 10.1128/msphere.00441-23. Epub 2023 Oct 18.
4
Evolution, persistence, and host adaption of a gonococcal AMR plasmid that emerged in the pre-antibiotic era.在抗生素出现之前就已经出现的淋球菌 AMR 质粒的进化、持续存在和宿主适应。
PLoS Genet. 2023 May 15;19(5):e1010743. doi: 10.1371/journal.pgen.1010743. eCollection 2023 May.
5
WGS of Commensal Reveals Acquisition of a New Ribosomal Protection Protein (MsrD) as a Possible Explanation for High Level Azithromycin Resistance in Belgium.共生菌的全基因组测序揭示了一种新的核糖体保护蛋白（MsrD）的获得，这可能是比利时阿奇霉素高水平耐药的原因。
Pathogens. 2021 Mar 23;10(3):384. doi: 10.3390/pathogens10030384.
6
Increasing Incidence of High-Level Tetracycline-Resistant Neisseria gonorrhoeae due to Clonal Spread and Foreign Import.由于克隆传播和国外输入，耐四环素淋病奈瑟菌的高耐药率发病率不断上升。
Yonsei Med J. 2016 Mar;57(2):350-7. doi: 10.3349/ymj.2016.57.2.350.
7
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future.21世纪淋病奈瑟菌的抗菌药物耐药性：过去、演变及未来
Clin Microbiol Rev. 2014 Jul;27(3):587-613. doi: 10.1128/CMR.00010-14.
8
Conjugative plasmids of Neisseria gonorrhoeae.淋病奈瑟菌的结合质粒。
PLoS One. 2010 Apr 1;5(4):e9962. doi: 10.1371/journal.pone.0009962.
9
Acquired macrolide resistance genes in pathogenic Neisseria spp. isolated between 1940 and 1987.1940年至1987年间分离出的致病性奈瑟菌属中获得的大环内酯类耐药基因。
Antimicrob Agents Chemother. 2003 Dec;47(12):3877-80. doi: 10.1128/AAC.47.12.3877-3880.2003.
10
Identification of tet(B), encoding high-level tetracycline resistance, in Neisseria meningitidis.在脑膜炎奈瑟菌中鉴定出编码高水平四环素抗性的tet(B)。
Antimicrob Agents Chemother. 2002 Dec;46(12):4045-6. doi: 10.1128/AAC.46.12.4045-4046.2002.
本文引用的文献
1
Intraspecific and intergeneric mobilization of non-conjugative resistance plasmids by a 24.5 megadalton conjugative plasmid of Neisseria gonorrhoeae.淋病奈瑟菌24.5兆道尔顿接合性质粒介导的非接合性耐药质粒的种内和属间转移
J Gen Microbiol. 1981 Jul;125(1):123-9. doi: 10.1099/00221287-125-1-123.
2
Heterogeneity of tetracycline resistance determinants in Streptococcus.链球菌中四环素抗性决定因素的异质性
J Bacteriol. 1982 Mar;149(3):995-1004. doi: 10.1128/jb.149.3.995-1004.1982.
3
Conjugation of plasmids of Neisseria gonorrhoeae to other Neisseria species: potential reservoirs for the beta-lactamase plasmid.淋病奈瑟菌质粒与其他奈瑟菌属菌种的接合：β-内酰胺酶质粒的潜在储存库。
J Infect Dis. 1984 Sep;150(3):397-401. doi: 10.1093/infdis/150.3.397.
4
Dissemination of the tetM tetracycline resistance determinant to Ureaplasma urealyticum.四环素抗性决定子tetM向解脲脲原体的传播。
Antimicrob Agents Chemother. 1986 Feb;29(2):350-2. doi: 10.1128/AAC.29.2.350.
5
Cloning and characterization of tetM gene from a Ureaplasma urealyticum strain.解脲脲原体菌株tetM基因的克隆与鉴定
Antimicrob Agents Chemother. 1987 Nov;31(11):1852-4. doi: 10.1128/AAC.31.11.1852.
6
Frequency and distribution in the United States of strains of Neisseria gonorrhoeae with plasmid-mediated, high-level resistance to tetracycline.美国具有质粒介导的对四环素高水平耐药性的淋病奈瑟菌菌株的频率及分布情况
J Infect Dis. 1987 Apr;155(4):819-22. doi: 10.1093/infdis/155.4.819.
7
High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant.淋病奈瑟菌的高水平四环素耐药性是获得链球菌tetM决定簇的结果。
Antimicrob Agents Chemother. 1986 Nov;30(5):664-70. doi: 10.1128/AAC.30.5.664.
8
Conjugal transfer of beta-lactamase-producing plasmids of Neisseria gonorrhoeae to Neisseria meningitidis.淋病奈瑟菌产β-内酰胺酶质粒向脑膜炎奈瑟菌的接合转移
Microbiol Immunol. 1986;30(8):737-42. doi: 10.1111/j.1348-0421.1986.tb03000.x.
9
Tetracycline-resistant Mycoplasma hominis strains contain streptococcal tetM sequences.耐四环素人型支原体菌株含有链球菌tetM序列。
Antimicrob Agents Chemother. 1985 Jul;28(1):141-3. doi: 10.1128/AAC.28.1.141.
10
Detection of specific sequences among DNA fragments separated by gel electrophoresis.在通过凝胶电泳分离的DNA片段中检测特定序列。
J Mol Biol. 1975 Nov 5;98(3):503-17. doi: 10.1016/s0022-2836(75)80083-0.
Zotero 插件