针刺治疗多囊卵巢综合征糖脂代谢紊乱的系统评价方案
Acupuncture for glucose and lipid metabolic disorders of polycystic ovarian syndrome: A systematic review protocol.
机构信息
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, P.R. China.
Department of Traditional Chinese Medicine, Chengdu Second People's Hospital, Chengdu, Sichuan, P.R. China.
出版信息
PLoS One. 2021 Aug 5;16(8):e0255732. doi: 10.1371/journal.pone.0255732. eCollection 2021.
BACKGROUND
Polycystic ovary syndrome (PCOS) is a common gynecological disease that is often accompanied by some metabolic abnormality such as insulin resistance and dyslipidemia. As a non-pharmacological therapy, acupuncture is widely used for the treatment of PCOS, but the effectiveness for insulin resistance and lipid metabolic disorder remains controversial.
OBJECTIVES
To assess the effectiveness and safety of acupuncture for insulin resistance and lipid metabolic disorder of women with PCOS.
SEARCH METHODS
Eight databases will be searched from inception to June 2021, three clinical trial registration platforms will be searched for relevant trials.
SELECTION CRITERIA
Randomized controlled trials (RCTs) of acupuncture therapy for insulin resistance and lipid metabolic of PCOS will be included.
DATA COLLECTION AND ANALYSIS
Study screening, data collection, and analysis will be performed by two or more reviewers independently. We will calculate mean difference (MD), standard mean difference (SMD) with 95% confidence intervals (CIs). Data synthesis will be performed with RevMan V.5.3 software and with Stata V.15.0 software when necessary.
PROSPERO REGISTRATION NUMBER
CRD42020177846.
背景
多囊卵巢综合征（PCOS）是一种常见的妇科疾病，常伴有胰岛素抵抗和血脂异常等代谢异常。作为一种非药物治疗方法，针灸广泛用于治疗 PCOS，但对于胰岛素抵抗和脂代谢紊乱的疗效仍存在争议。
目的
评估针灸治疗 PCOS 患者胰岛素抵抗和脂代谢紊乱的疗效和安全性。
检索方法
检索从建库到 2021 年 6 月的 8 个数据库，并在 3 个临床试验注册平台上搜索相关试验。
选择标准
纳入针灸治疗 PCOS 胰岛素抵抗和脂代谢的随机对照试验（RCT）。
数据收集和分析
由两名或多名评审员独立进行研究筛选、数据收集和分析。我们将计算均数差（MD）、95%置信区间（CI）的标准均数差（SMD）。必要时使用 RevMan V.5.3 软件和 Stata V.15.0 软件进行数据综合。
前瞻性注册编号
CRD42020177846。
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