Intensive Care Unit, Wuhan Jinyintan Hospital, Wuhan, China.
Department of Tuberculosis, Wuhan Jinyintan Hospital, Wuhan, China.
Ann Palliat Med. 2021 Jul;10(7):7543-7550. doi: 10.21037/apm-21-1178.
This study was carried out based on the background that pulmonary tuberculosis seriously threatens people's physical health while the current treatment has certain limitations.
A total of 150 patients with pulmonary tuberculosis who were admitted to Wuhan Jinyintan Hospital from January 2017 to December 2018 were selected as study participants. Patients were randomly divided into a control group (n=75) who were treated with routine nursing, and an experimental group (n=75) who were treated with comprehensive nursing intervention combined with respiratory functional exercises. Following treatment, the pulmonary function, self-care ability, and other indexes of the patients in both groups were compared and analyzed.
After nursing intervention, the pulmonary function and self-care ability of patients in the experimental group were significantly higher than those in the control group. The scores of the 6-minute walking distance (6MWD) and modified Medical Research Council (mMRC) dyspnea scale of patients in both groups were significantly higher after nursing intervention compared to before intervention. Furthermore, after intervention, the scores in the experimental group were significantly higher than those in the control group. The partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2), and the quality of life of patients in the experimental group after intervention were significantly better than those in the control group.
Comprehensive nursing intervention combined with respiratory functional exercises can significantly improve the pulmonary function, self-care ability, and quality of life of patients with pulmonary tuberculosis, with obvious clinical efficacy.
Chinese Clinical Trial Registry ChiCTR2100048983.
本研究基于这样的背景：肺结核严重威胁着人们的身体健康，而目前的治疗方法存在一定的局限性。
选取 2017 年 1 月至 2018 年 12 月期间在武汉金银潭医院收治的 150 例肺结核患者作为研究对象。将患者随机分为对照组（n=75）和实验组（n=75），对照组采用常规护理，实验组在常规护理的基础上联合呼吸功能锻炼进行综合护理干预。治疗后，比较并分析两组患者的肺功能、自理能力等指标。
护理干预后，实验组患者的肺功能和自理能力明显高于对照组。两组患者的 6 分钟步行距离（6MWD）和改良医学研究委员会（mMRC）呼吸困难评分均明显高于护理干预前，且实验组干预后的评分明显高于对照组。干预后，实验组患者的血氧分压（PaO2）、二氧化碳分压（PaCO2）和生活质量明显优于对照组。
综合护理干预联合呼吸功能锻炼可明显改善肺结核患者的肺功能、自理能力和生活质量，具有显著的临床疗效。
中国临床试验注册中心 ChiCTR2100048983。
