Faull R J, Aarons I, Woodroffe A J, Clarkson A R
Royal Adelaide Hospital, SA.
Aust N Z J Med. 1987 Aug;17(4):396-401. doi: 10.1111/j.1445-5994.1987.tb00072.x.
A retrospective study was performed of all patients at the Royal Adelaide Hospital over a ten-year period with biopsy proven Henoch-Schönlein nephritis. The records of 27 patients were examined, with emphasis on clinical and histopathological presentation, treatment and outcome. A scheme for assessing glomerular histology is presented, and severity correlated with prognosis of the disease. At presentation unfavourable prognostic indicators were acute renal impairment, crescents in greater than 20% of glomeruli, and severe glomerular histological lesions. Four patients died as a result of the disease, and 20 of the patients had evidence of continued renal abnormality at follow-up. Adult Henoch-Schönlein nephritis is a potentially catastrophic disease, and requires careful assessment at presentation.
对皇家阿德莱德医院10年间经活检证实为过敏性紫癜性肾炎的所有患者进行了一项回顾性研究。检查了27例患者的记录，重点关注临床和组织病理学表现、治疗及结果。提出了一种评估肾小球组织学的方案，并将严重程度与疾病预后相关联。就诊时，不良预后指标包括急性肾功能损害、超过20%的肾小球出现新月体以及严重的肾小球组织学病变。4例患者死于该病，20例患者在随访时有持续肾脏异常的证据。成人过敏性紫癜性肾炎是一种潜在的灾难性疾病，就诊时需要仔细评估。
