Alharbi Najwa M, Ziadi Mashayed M
College of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
King Abdulaziz University, Jeddah, Saudi Arabia.
Saudi J Biol Sci. 2021 Aug;28(8):4358-4364. doi: 10.1016/j.sjbs.2021.04.025. Epub 2021 Apr 16.
Antibiotic resistance is a common and serious public health worldwide. As an alternative to antibiotics, bacteriophage (phage) therapy offers one of the best solutions to antibiotic resistance. Bacteriophages survive where their bacterial hosts are found; thus, they exist in almost all environments and their applications are quite varied in the medical, environmental, and industrial fields. Moreover, a single phage or a mixture of phages can be used in phage therapy; mixed phages tend to be more effective in reducing the number and/or activity of pathogenic bacteria than that of a single phage.
抗生素耐药性是全球范围内常见且严重的公共卫生问题。作为抗生素的替代方法,噬菌体疗法为抗生素耐药性提供了最佳解决方案之一。噬菌体在其细菌宿主存在的地方存活;因此,它们几乎存在于所有环境中,并且在医学、环境和工业领域有相当广泛的应用。此外,在噬菌体疗法中可以使用单一噬菌体或噬菌体混合物;与单一噬菌体相比,混合噬菌体在减少病原菌数量和/或活性方面往往更有效。