Wexler Tanja Lundholm Rasmussen, Novovic Srdan, Lauritsen Morten Laksafoss, Hansen Erik Feldager, Schmidt Palle Nordblad, Karstensen John Gásdal
Ugeskr Laeger. 2021 Jul 19;183(29).
Acute necrotising pancreatitis is a condition associated with high morbidity and mortality, and for decades surgical intervention was the gold standard for treatment of symptomatic pancreatic necrosis. A shift towards minimally invasive interventions has reduced the mortality significantly as summarised in this review. Studies comparing open necrosectomy with videoscopic-assisted retroperitoneal debridement (VARD) have demonstrated that VARD lowers morbidity and mortality. When endoscopic therapy is impossible, VARD is recommended as the preferred surgical intervention for symptomatic necrotising pancreatitis.
急性坏死性胰腺炎是一种发病率和死亡率都很高的疾病，几十年来，手术干预一直是有症状胰腺坏死治疗的金标准。正如本综述所总结的，向微创干预的转变显著降低了死亡率。比较开放坏死组织清除术与电视辅助腹膜后清创术（VARD）的研究表明，VARD可降低发病率和死亡率。当无法进行内镜治疗时，推荐VARD作为有症状坏死性胰腺炎的首选手术干预方法。
