Eickhoff R M, Steinbusch J, Seppelt P, Kroh A, Junge K, Klink C D, Neumann U P, Binnebösel M
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Uniklinik RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
Klinik für Allgemein-, Viszeral- und Minimalinvasive Chirurgie, Medizinisches Zentrum der Städte Region Aachen, Aachen, Deutschland.
Chirurg. 2017 Sep;88(9):785-791. doi: 10.1007/s00104-017-0377-4.
Among patients with necrotizing pancreatitis 15-20% develop infected necrosis, which entails mortality rates of up to 20%. Particularly driven by the results of the Dutch Pancreatitis Study Group there has been a paradigm change from open necrosectomy to step-up treatment with initial percutaneous and/or endoscopic drainage followed, if necessary, by minimally invasive retroperitoneal debridement.
Description of case series in which patients underwent video-assisted retroperitoneal debridement (VARD) including follow-up focused on quality of life.
Systematic cohort study including all patients who underwent a VARD procedure at the Department of General, Visceral and Transplantation Surgery at Aachen University Hospital from 2011 to 2015. Quality of life was recorded using the EORTC QLQ-C 30 questionnaire and compared to a representative sample of the German general population.
The VARD procedure was performed in 9 cases, although in 1 case conversion to an open approach due to an acute bleeding was necessary. There was no 30-day and 60-day mortality following VARD. During the postoperative stay no patient required specific treatment for surgical complications. In particular, no enterocutaneous fistula or organ perforation was observed. Regarding the quality of life score there was no significant difference concerning the global health status, compared to the sample from the general population.
Our data reinforce that a step-up approach in patients with necrotizing pancreatitis is a feasible and safe treatment procedure. For the first time, we could demonstrate satisfactory results in a long-term follow-up including QOL.
在坏死性胰腺炎患者中,15% - 20%会发展为感染性坏死,其死亡率高达20%。特别是在荷兰胰腺炎研究小组的研究结果推动下,治疗模式已从开放性坏死组织清除术转变为逐步治疗,即先进行经皮和/或内镜引流,必要时再进行微创腹膜后清创术。
描述一系列患者接受视频辅助腹膜后清创术(VARD)的病例,并重点关注生活质量的随访情况。
进行系统队列研究,纳入2011年至2015年在亚琛大学医院普通、内脏和移植外科接受VARD手术的所有患者。使用欧洲癌症研究与治疗组织(EORTC)QLQ - C 30问卷记录生活质量,并与德国普通人群的代表性样本进行比较。
共进行了9例VARD手术,不过有1例因急性出血而转为开放手术。VARD术后30天和60天均无死亡病例。术后住院期间,无患者因手术并发症需要特殊治疗。特别是未观察到肠皮肤瘘或器官穿孔。在生活质量评分方面,与普通人群样本相比,总体健康状况无显著差异。
我们的数据进一步证明,坏死性胰腺炎患者采用逐步治疗方法是一种可行且安全的治疗程序。我们首次在包括生活质量的长期随访中取得了令人满意的结果。