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[卡塔尼亚省感染风险人群及献血者中抗LAV/HTLV III抗体的流行情况]

[Prevalence of anti-LAV/HTLV III antibodies in groups at risk of infection and in donors blood in the province of Catania].

作者信息

Mauro L, Ciccia M, Romeo M A, Di Gregorio F, Sciacca S, Maccarrone S

机构信息

Istituto di Igiene e Medicina Preventiva, Università degli Studi di Catania.

出版信息

Boll Ist Sieroter Milan. 1987;66(3):194-7.

PMID:3435650
Abstract

The prevalence of anti-LAV/HTLV III antibodies in serum samples of individuals at high risk for AIDS and of healthy individuals living in the province of Catania is reported. Serum samples were collected over the period 1983-86 from 220 drug addicts adults, 339 from multitransfused thalassemia patients, 71 from hemophiliacs, 22 from subjects of the hospital staff who had had contacts with positive subjects, 9 from family contacts of positive multitransfused thalassemics and 7270 from blood donors. Prevalence of antibodies among drug addicts was 14% and a positive subject was found as early as 1983. This result suggested that LAV/HTLV III was already present in Catania at that year. Among the thalassemics and the hemophiliacs the prevalence was 2.3% and 21% respectively. No positive subject was found among hospital staff nor among family contacts of positive thalassemic subjects. Three positive cases have been found among the blood donors and even though these are drug addicts, it is important to underline the necessity of a regular screening of the blood units to prevent LAV/HTLV III diffusion.

摘要

报告了卡塔尼亚省艾滋病高危个体和健康个体血清样本中抗LAV/HTLV III抗体的流行情况。1983年至1986年期间收集了血清样本,其中包括220名成年吸毒者、339名多次输血的地中海贫血患者、71名血友病患者、22名与阳性患者有接触的医院工作人员、9名多次输血的地中海贫血阳性患者的家庭接触者以及7270名献血者。吸毒者中抗体流行率为14%,早在1983年就发现了一名阳性个体。这一结果表明,当年LAV/HTLV III已在卡塔尼亚存在。在地中海贫血患者和血友病患者中,流行率分别为2.3%和21%。在医院工作人员和地中海贫血阳性患者的家庭接触者中未发现阳性个体。在献血者中发现了3例阳性病例,尽管这些献血者是吸毒者,但必须强调定期筛查血液单位以防止LAV/HTLV III传播的必要性。

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