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泰国特定人群中人类嗜T淋巴细胞病毒III型/淋巴腺病相关病毒抗体的流行情况。

Prevalence of HTLV-III/LAV antibody in selected populations in Thailand.

作者信息

Wangroongsarb Y, Weniger B G, Wasi C, Traisupa A, Kunasol P, Rojanapithayakorn W, Fucharoen S

出版信息

Southeast Asian J Trop Med Public Health. 1985 Dec;16(4):517-20.

PMID:3869739
Abstract

Antibody to the human T-lymphotropic virus, type III/lymphadenopathy-associated virus (HTLV-III/LAV) by ELISA test was detected in one (1%) of 101 male homosexual prostitutes (confidence limit 95%:0.03-5.4%, in two (2%) of 100 thalassemia patients, and in none (C.L. 95%:0-3.6%) of 100 female prostitutes, 99 parenteral drug abusers, 100 male VD patients, 100 consecutive blood donors in serum collected from February through June 1985. Serum from the positive homosexual subject was strongly positive on repeated ELISA testing, and was also positive by Western Blot test. The two thalassemia patients, who were repeatedly weakly-positive by ELISA, were negative by Western Blot test and presumed to be false positive reactors. Prevalence of HTLV-III/LAV virus in sexually-active homosexuals in Thailand in 1985 appears to be similar to the 1% rate among homosexuals in San Francisco in 1978 at the start of the AIDS epidemic there.

摘要

通过酶联免疫吸附测定(ELISA)检测人类嗜T淋巴细胞病毒III型/淋巴结病相关病毒(HTLV-III/LAV)抗体,结果显示,在101名男性同性恋妓女中有1人(1%)检测呈阳性(95%置信区间:0.03 - 5.4%),在100名地中海贫血患者中有2人(2%)检测呈阳性,而在100名女性妓女、99名注射毒品者、100名男性性病患者以及1985年2月至6月采集血清的100名连续无偿献血者中均无人检测呈阳性(95%置信区间:0 - 3.6%)。那名检测呈阳性的同性恋者的血清在重复ELISA检测中呈强阳性,在蛋白质印迹法检测中也呈阳性。两名地中海贫血患者的血清在ELISA检测中多次呈弱阳性,但在蛋白质印迹法检测中呈阴性,推测为假阳性反应者。1985年泰国性活跃同性恋者中HTLV-III/LAV病毒的流行率似乎与1978年艾滋病在旧金山开始流行时同性恋者中1%的感染率相似。

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