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为什么在眼科中使用超短脉冲,以及哪些因素会影响切割质量。

Why Use Ultrashort Pulses in Ophthalmology and Which Factors Affect Cut Quality.

机构信息

Eye Clinic ORASIS, Swiss Eye Research Foundation, 5734 Reinach AG, Switzerland.

Department of Physics, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovica 4, 21000 Novi Sad, Serbia.

出版信息

Medicina (Kaunas). 2021 Jul 8;57(7):700. doi: 10.3390/medicina57070700.

Abstract

The power density of femtosecond lasers and exposure time to the tissue are crucial for a successful procedure in terms of safety and precision. The reduction of the pulse duration allows reducing the quantity of the energy to be delivered to the tissue for disruption with strongly diminished mechanical and thermal collateral damage. The cutting effect of ultra-short pulses is very precise, minimally traumatic, safe, and predictable. Future developments will lead to further energy reductions to achieve optical breakdowns. However, the pulse length cannot be shortened arbitrarily because below 100 fs nonlinear effects can change the process in an unfavorable way. Compared to manual-conventional cataract surgery, femtosecond laser-assisted cataract surgery (FLACS) shows many advantages in clinical application, especially with regard to precision and tissue protection. The femtosecond laser has become particularly important and has made the overall procedure safer when we deal with complex cataract cases such as subluxated lenses. We provide an overview of the evolution of femtosecond laser technology for use in refractive and cataract surgeries. This article describes the advantages of available laser platforms with ultrashort pulses and mainly focuses on the technical and physical backgrounds of ophthalmic surgery technologies.

摘要

飞秒激光的功率密度和对组织的照射时间对于手术的安全性和精确性至关重要。缩短脉宽可以减少传递到组织的能量,从而大大减少机械和热的附带损伤。超短脉冲的切割效果非常精确、微创、安全且可预测。未来的发展将进一步降低能量以实现光击穿。然而,脉冲长度不能任意缩短,因为在 100fs 以下,非线性效应可能会以不利的方式改变这个过程。与手动传统白内障手术相比,飞秒激光辅助白内障手术(FLACS)在临床应用中具有许多优势,特别是在精确性和组织保护方面。当我们处理复杂的白内障病例,如晶状体半脱位时,飞秒激光变得尤为重要,并使整个手术过程更加安全。我们概述了飞秒激光技术在屈光和白内障手术中的应用发展。本文介绍了具有超短脉冲的可用激光平台的优势,并主要侧重于眼科手术技术的技术和物理背景。

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