Department of Ophthalmology, Basel University Hospital, Mittlerestr str. 91, 4056 Basel, Switzerland.
Division of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, 1205 Geneva, Switzerland.
Sensors (Basel). 2021 Feb 2;21(3):996. doi: 10.3390/s21030996.
Femtosecond laser-assisted cataract surgery has the potential to make critical steps of cataract surgery easier and safer, and reduce endothelial cell loss, thus, improving postoperative outcomes. This study compared FLACS with the conventional method in terms of endothelial cells behavior, clinical outcomes, and capsulotomy precision.
In a single-center, randomized controlled study, 130 patients with cataracta senilis received FLACS or conventional cataract surgery.
A significant endothelial cell loss was observed postoperatively, compared to the preoperative values in both groups. The endothelial cell counts was significantly better in the FLACS group in cataract grade 2 ( = 0.048) patients, compared to conventionally at 4 weeks. The effective phaco time was notably shorter in grade 2 of the FLACS group ( = 0.007) compared to the conventional. However, no statistically significant differences were found for the whole sample, including all cataract grades, due to the overall cataract density in the FLACS group being significantly higher (2.60 ± 0.58, < 0.001) as compared to conventional methods (2.23 ± 0.42).
Low energy FLACS provides a better result compared to endothelial cell loss, size, and shape variations, as well as in effective phaco time within certain cataract grade subgroups. A complete comparison between two groups was not possible because of the higher cataract grade in the FLACS. FLACS displayed a positive effect on endothelial cell preservation and was proven to be much more precise.
飞秒激光辅助白内障手术有可能使白内障手术的关键步骤更容易和更安全，并减少内皮细胞损失，从而改善术后结果。本研究比较了飞秒激光辅助白内障手术（FLACS）与传统方法在角膜内皮细胞行为、临床结果和囊袋切开精度方面的差异。
在一项单中心、随机对照研究中，130 名老年性白内障患者接受了 FLACS 或传统白内障手术。
与两组术前值相比，术后均观察到明显的内皮细胞丢失。与传统组相比，FLACS 组白内障 2 级（ = 0.048）患者术后内皮细胞计数明显更好，4 周时差异有统计学意义。FLACS 组 2 级的有效超声乳化时间明显短于传统组（ = 0.007）。然而，由于 FLACS 组的整体白内障密度明显高于传统组（2.60 ± 0.58， < 0.001），包括所有白内障分级在内的全样本并没有表现出统计学上的显著差异。
低能量的飞秒激光辅助白内障手术在某些白内障分级亚组中，在角膜内皮细胞丢失、大小和形状变化以及有效超声乳化时间方面提供了更好的结果。由于 FLACS 组的白内障分级较高，无法对两组进行完全比较。FLACS 对内皮细胞的保护有积极的影响，并且被证明更加精确。
