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[冷适应动物对高氧暴露敏感性的生化指标]

[Biochemical indices of the sensitivity of cold-adapted animals to hyperoxic exposure].

作者信息

Goroshinskaia I A, Ananian A A, Shugaleĭ V S, Krichevskaia A A

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(11):54-9.

PMID:3435732
Abstract

It has been established that white rats adapted to the low temperature of the environment (45 days 2-4 degrees C) in contrast to the animals undergoing such action during 3 days (cold stress) show resistance to the toxic action of the high oxygen pressure. The considerable removal of convulsions under the action of oxygen, the absence of increase of erythrocyte membrane permeability in the preconvulsive stage of hyperoxia and prevention of changes in the substrate specificity of type A monoamine oxidase both in preconvulsive and convulsive periods of oxygen intoxication are their characteristics.

摘要

已经确定,与在3天内经历这种作用(冷应激)的动物相比,适应环境低温(45天,2-4摄氏度)的白鼠对高氧压力的毒性作用表现出抗性。在氧气作用下惊厥明显减轻、在高氧惊厥前期红细胞膜通透性没有增加以及在氧气中毒的惊厥前期和惊厥期均能防止A型单胺氧化酶底物特异性的变化是它们的特征。

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