Rockoff A, Spigland I, Lorenstein B, Rose A L
Ann Neurol. 1979 Jan;5(1):99-101. doi: 10.1002/ana.410050116.
A 5-year-old girl developed a progressive febrile neurological illness consisting of right focal seizures, right hemiparesis, and stupor evolving over a period of six weeks. During the month preceding the onset of her illness she had received two apparently unsuccessful smallpox vaccinations without a skin lesion. Elevation of cerebrospinal fluid gamma globulin and findings on brain biopsy were consistent with postinfectious encephalitis, and a simultaneous increase in serum vaccinia antibody titer suggested that the illness was postvaccinial encephalitis. Clinically, the child developed a severe extrapyramidal movement disorder during the acute phase followed by nine months of stuporous unresponsiveness, yet subsequently made a substantial recovery.
一名5岁女孩患上了一种进行性发热性神经系统疾病，包括右侧局灶性癫痫发作、右侧偏瘫和昏迷，病程持续了六周。在发病前一个月，她接种了两次天花疫苗，但均未出现皮肤损伤，且接种似乎未成功。脑脊液γ球蛋白升高以及脑活检结果符合感染后脑炎，同时血清牛痘抗体滴度升高表明该疾病为接种后脑炎。临床上，患儿在急性期出现了严重的锥体外系运动障碍，随后九个月处于昏迷无反应状态，但后来有了显著恢复。
