Department of Neonatal Intensive Care, CHR Sambre et Meuse, Namur, Belgium.
Follow-up Center for preterm infants, CHR Sambre et Meuse, Namur, Belgium.
Int J Gynaecol Obstet. 2021 Dec;155(3):490-495. doi: 10.1002/ijgo.13859. Epub 2021 Sep 8.
To examine the impact of the coronavirus disease 2019 (COVID-19) pandemic and the resulting isolation measures on the risk of postpartum depression (PPD) after preterm birth.
This is a cross-sectional study of mothers of extreme and early preterm infants who completed the Edinburgh Postnatal Depression Scale (EPDS) at the standardized 3-6 months follow-up consultation for preterm infants. Mothers assessed during the COVID-19 pandemic (n = 34; from April 1, 2020 to March 31, 2021) were compared with an antecedent control group (n = 108; from January 1, 2017 to December 31, 2019). A multivariable logistic regression model was used to examine the relationship between the pandemic and the risk of PPD (EPDS score ≥13).
The prevalence of depressive symptoms was significantly higher in the COVID-19 study group (26% versus 12%, P = 0.043). The multivariable logistic regression model showed a significant association between the COVID-19 pandemic and the risk of PPD (adjusted odds ratio 3.60, 95% confidence interval 1.06-12.59, P = 0.040).
Among mothers of extreme and early preterm infants, the COVID-19 pandemic was independently associated with a higher risk of PPD. This confirms the need for a close and long-term follow up of maternal psychological health after preterm birth.
探讨 2019 年冠状病毒病（COVID-19）大流行及其导致的隔离措施对早产产后抑郁症（PPD）风险的影响。
这是一项横断面研究，纳入了在早产儿标准化 3-6 个月随访就诊时完成爱丁堡产后抑郁量表（EPDS）的极早早产儿和早期早产儿的母亲。评估了 COVID-19 大流行期间（n=34；从 2020 年 4 月 1 日至 2021 年 3 月 31 日）的母亲，并与前一个对照组（n=108；从 2017 年 1 月 1 日至 2019 年 12 月 31 日）进行比较。采用多变量逻辑回归模型来研究大流行与 PPD 风险（EPDS 评分≥13）之间的关系。
COVID-19 研究组的抑郁症状发生率明显更高（26%对 12%，P=0.043）。多变量逻辑回归模型显示，COVID-19 大流行与 PPD 风险之间存在显著关联（调整后的优势比 3.60，95%置信区间 1.06-12.59，P=0.040）。
在极早早产儿和早期早产儿的母亲中，COVID-19 大流行与 PPD 风险增加独立相关。这证实了在早产分娩后需要密切和长期随访产妇的心理健康。
