神经肽 - 多巴胺相互作用。I. 环（组氨酸 - 脯氨酸）介导的大鼠体温过低中的多巴胺能机制。
Neuropeptide-dopamine interactions. I. Dopaminergic mechanisms in cyclo(His-Pro)-mediated hypothermia in rats.
作者信息
Prasad C
机构信息
Department of Medicine, Louisiana State University Medical Center, New Orleans 70112.
出版信息
Brain Res. 1987 Dec 29;437(2):345-8. doi: 10.1016/0006-8993(87)91649-0.
PMID:3435841
Abstract
Administration of cyclo(His-Pro) to rats produces a dose-dependent hypothermia that is attenuated by dopaminergic antagonists. Chronic treatment with cyclo(His-Pro) potentiates hypothermia induced by apomorphine. These results suggest that cyclo(His-Pro) acts via a dopaminergic mechanism to modulate body temperature.
摘要
给大鼠注射环（组氨酸-脯氨酸）会产生剂量依赖性体温过低，多巴胺能拮抗剂可减弱这种作用。长期用环（组氨酸-脯氨酸）治疗可增强阿扑吗啡诱导的体温过低。这些结果表明，环（组氨酸-脯氨酸）通过多巴胺能机制来调节体温。
Zotero 插件