Provincial Programs, BC Cancer, 750 West Broadway, Vancouver, BC, V5Z 1H5, Canada. Electronic address: https://twitter.com/@_sarahweller.
Cancer and Palliative Care Outcomes Centre, Queensland University of Technology, 191 Ipswich Rd, Woolloongabba, QLD, 4102, Australia; Exercise Medicine Research Institute, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA, 6027, Australia; Institute for Health Research, University of Notre Dame Australia, 23 High Street, Freemantle, WA, 6160, Australia. Electronic address: https://twitter.com/@DrNicolasHart.
Crit Rev Oncol Hematol. 2021 Oct;166:103433. doi: 10.1016/j.critrevonc.2021.103433. Epub 2021 Aug 3.
Exercise has the potential to improve physical function and quality of life in individuals with bone metastases but is often avoided due to safety concerns. This systematic review summarizes the safety, feasibility and efficacy of exercise in controlled trials that include individuals with bone metastases.
MEDLINE, Embase, Pubmed, CINAHL, PEDro and CENTRAL databases were searched to July 16, 2020.
A total of 17 trials were included incorporating aerobic exercise, resistance exercise or soccer interventions. Few (n = 4, 0.5%) serious adverse events were attributed to exercise participation, with none related to bone metastases. Mixed efficacy results were found, with exercise eliciting positive changes or no change. The majority of trials included an element of supervised exercise instruction (n = 16, 94%) and were delivered by qualified exercise professionals (n = 13, 76%).
Exercise appears safe and feasible for individuals with bone metastases when it includes an element of supervised exercise instruction.
运动有改善骨转移患者身体功能和生活质量的潜力，但由于安全性问题，往往被回避。本系统综述总结了包含骨转移患者的对照试验中运动的安全性、可行性和疗效。
检索了 MEDLINE、Embase、PubMed、CINAHL、PEDro 和 CENTRAL 数据库，截至 2020 年 7 月 16 日。
共纳入了 17 项试验，包括有氧运动、抗阻运动或足球干预。很少有（n=4，0.5%）严重不良事件归因于运动参与，没有与骨转移相关的事件。运动产生了积极的变化或没有变化，混合疗效结果。大多数试验都包含了监督运动指导的内容（n=16，94%），并且由合格的运动专业人员进行了运动指导（n=13，76%）。
当包含监督运动指导的内容时，运动对骨转移患者是安全且可行的。
