泌尿系统疾病中糖胺聚糖的尿排泄情况。

Urinary excretion of glycosaminoglycans in urological disease.

作者信息

Baggio B, Gambaro G, Cicerello E, Mastrosimone S, Marzaro G, Borsatti A, Pagano F

机构信息

Institute of Internal Medicine, University of Padova, Italy.

出版信息

Clin Biochem. 1987 Dec;20(6):449-50. doi: 10.1016/0009-9120(87)90013-0.

DOI:10.1016/0009-9120(87)90013-0

PMID:3436040

Abstract

Altered urinary excretion of glycosaminoglycans (GAG) has been reported in patients with nephrolithiasis, with chronic glomerulonephritis, and incipient diabetic nephropathy, but evaluation of urinary GAG has not been reported in infections and proliferating diseases of the urinary tract. Urinary excretion of GAG was measured in 50 patients with idiopathic calcium nephrolithiasis (ICN) of whom 20 had associated urinary tract infection, in 20 subjects with recurrent infection of the urinary tract (UTI), and in 18 patients with bladder papillomatosis. Mean values were significantly lower in ICN, increased in papillomatosis, and in the normal range in UTI.

摘要

据报道，肾结石患者、慢性肾小球肾炎患者及早期糖尿病肾病患者的尿中糖胺聚糖（GAG）排泄量会发生改变，但尚未见有关泌尿道感染和增殖性疾病患者尿GAG评估的报道。对50例特发性钙肾结石（ICN）患者（其中20例伴有泌尿道感染）、20例复发性泌尿道感染（UTI）患者及18例膀胱乳头状瘤患者的尿GAG排泄量进行了测定。ICN患者的平均值显著降低，乳头状瘤患者的平均值升高，UTI患者的平均值在正常范围内。